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http://dx.doi.org/10.2174/1567201820666230210161253 | DOI Listing |
Environ Int
September 2025
Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Anhui Medical University, Hefei, China; Department of Toxicology, School of Public Health, Anhui Medical University, Hefei, China. Electronic address:
Cadmium (Cd) is a respiratory toxicant. Previous reports have confirmed that chronic respiratory Cd exposure causes chronic obstructive pulmonary disease-like lesions in a murine model. This study aimed to evaluate the influence of short-term Cd exposure on lung function.
View Article and Find Full Text PDFEur Respir Rev
July 2025
Department of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, China
Background: Limited evidence exists on air pollution's systemic impact on lung function and mediating biomarkers. This study comprehensively evaluated associations between air pollution, COPD and lung function, while exploring biomarker mediation.
Methods: A prospective analysis of 451 566 UK Biobank participants was conducted.
J Biophotonics
September 2025
Department of Cell Biology and Anatomy, University of Calgary, Calgary, Alberta, Canada.
Intravital lung imaging has been employed to study physiological and pathophysiological processes related to nanoparticle deposition in the alveolar lung, particularly in the context of air pollution and drug delivery. However, optical imaging depth is limited, often attributed to the refractive index (RI) mismatch at the alveolar air-tissue interface. To investigate this, we evaluated two complementary strategies.
View Article and Find Full Text PDFRespir Res
August 2025
Center of Emergency and Critical Medicine, Jinshan Hospital of Fudan University, 1508 Longhang Rd, Shanghai, 201508, China.
Background: E-cigarette or vaping product use-associated Lung Injury (EVALI) has become a public health concern since 2019, with vitamin E acetate (VEA) identified as a potential causative agent. While previous studies have used whole-body VEA aerosol exposure or intratracheal instillation models, these approaches may introduce confounding exposure routes or do not fully reflect real-world vaping conditions. To better understand VEA-induced EVALI, there remains a need for an animal model that isolates airway exposure and closely mimics human vaping behaviour.
View Article and Find Full Text PDFYakugaku Zasshi
August 2025
Department of Pharmaceutics and Drug Delivery, Faculty of Pharmaceutical Sciences, Tokyo University of Science.
This review is a partial summary of the author's 40 years of research and development at Otsuka Pharmaceutical Co., Ltd. and the Faculty of Pharmaceutical Sciences, Tokyo University of Science.
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