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http://dx.doi.org/10.1111/1346-8138.16723 | DOI Listing |
Cureus
August 2025
Faculty of Health Sciences, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Recurrent dermatofibrosarcoma protuberans (DFSP) of the anterior chest wall in elderly patients presents a complex reconstructive challenge, necessitating approaches that balance oncological radicality with minimized morbidity and optimal tissue quality for potential adjuvant radiotherapy. We report the case of an 84-year-old woman with an eighth recurrence of chest wall DFSP. Following wide local excision with clear margins, a significant soft tissue defect remained.
View Article and Find Full Text PDFCureus
August 2025
Pathology and Laboratory Medicine, New York City Health and Hospitals Corporation (NYC HHC) Lincoln, Bronx, USA.
Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue sarcoma with a generally low risk for metastasis. Most individuals are diagnosed with this neoplasm in the third or fourth decade of life, with the growth usually being no larger than 5 cm in maximum diameter at the time of diagnosis. The majority of these patients are treated with wide local excision, with most experiencing no recurrence or metastasis.
View Article and Find Full Text PDFMod Pathol
September 2025
Department of Pathology, NYU Langone Health, New York, NY 10016, USA. Electronic address:
Dermatofibrosarcoma protuberans (DFSP) is a neoplasm of the dermis with a tendency for aggressive local growth and recurrence. A minority of DFSP cases may transform into higher-grade sarcoma (fibrosarcomatous transformation, FST-DFSP) which is associated with more aggressive behavior and risk of metastasis. The histologic diagnosis of FST-DFSP may be challenging, particularly in small biopsies.
View Article and Find Full Text PDFDermatol Surg
September 2025
Department of Medicine, Division of Dermatology, Washington University School of Medicine, St. Louis, Missouri.
J Cutan Pathol
September 2025
Department of Orthopedic Surgery, Osaka International Cancer Institute, Osaka, Japan.