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Background: Metastatic sarcoma confers a grave prognosis to patients and poses a management dilemma for clinicians. Pulmonary metastasectomy is frequently performed for the recurrence of sarcomatous tumours in the lung, but the evidence-base is poor. No guidelines exist to inform clinicians on appropriate patient selection and surgical technique.
Aim: This review aims to establish and analyse the most important prognostic factors for survival post pulmonary metastasectomy for recurrent sarcoma. We summarise the key tumour, peri-operative and patient characteristics that should guide surgical management.
Methods: A comprehensive search of the literature utilising OVID Medline and PubMed databases was conducted to identify all relevant research within the past 15 years. We evaluated all articles that specifically studied sarcoma patients (both bone and soft tissue).
Conclusion: Disease-free interval and tumour burden remain important prognostic factors, while tumour grade is likely not significant. VATS is a safe and viable alternative to thoracotomy without sacrificing survival outcomes. No single peri-operative characteristic provides useful prognostic information in isolation.
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http://dx.doi.org/10.1007/s11748-023-01905-y | DOI Listing |
Cureus
August 2025
Department of Thoracic Surgery, Attikon General Hospital, National and Kapodistrian University of Athens, Athens, GRC.
Left-sided partial anomalous pulmonary venous return (PAPVR) may remain clinically silent and undiagnosed until incidentally identified, potentially introducing complexity in perioperative assessment and management, particularly in patients with significant comorbidities. We report the case of a 77-year-old male with metastatic colorectal adenocarcinoma and a history of multiple right-sided pulmonary metastasectomies. He underwent a right completion upper bilobectomy.
View Article and Find Full Text PDFJ Surg Oncol
September 2025
Surgery, Keck School of Medicine of USC, Los Angeles, California, USA.
Background And Objectives: Minimally invasive (MI) pulmonary metastasectomy may improve access in frail patients who are at high-risk for complications after thoracotomy. We compared postoperative complications among frail and non-frail patients undergoing pulmonary metastasectomy.
Methods: The Nationwide Readmissions Database (2017-2019) identified adult patients who underwent pulmonary metastasectomy.
Int J Colorectal Dis
August 2025
Department of Colorectal Surgery, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang, China.
Purpose: Lung metastasectomy has been considered the cornerstone of treatment of resectable colorectal cancer pulmonary oligometastases (CRCPOM). However, the role of chemotherapy in the neoadjuvant setting remains unclear. This study aimed to determine whether neoadjuvant therapy (NAT) could further improve survival outcomes of patients with resectable CRCPOM.
View Article and Find Full Text PDFIndian J Thorac Cardiovasc Surg
September 2025
Department of Thoracic Oncosurgery, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, 110085 India.
Unlabelled: With advances in systemic anticancer therapies, pulmonary metastasectomy is being increasingly employed for local disease control while aiming to preserve lung parenchyma, anatomy, and function with complete (R0) resection. We introduce an innovative neodymium-doped yttrium aluminum garnet (Nd-YAG) light amplification by stimulated emission of radiation (LASER) approach for peripherally located, deep-seated, and fissural lesions, utilizing the lung's natural tongue-like configuration at the edges. This method involves cylindrical excision around the nodule, creating a buttonhole from one surface to the other.
View Article and Find Full Text PDFCancer Rep (Hoboken)
August 2025
Department of Urology, Teikyo University Hospital, Mizonokuchi, Kawasaki City, Japan.
Background: Urachal carcinoma (URC) is a rare tumor of the urinary bladder, of which the histology usually resembles that of colorectal adenocarcinoma. Achievement of cure in patients with metastatic URC is difficult, and the survival rate of these patients has remained unsatisfactory despite various efforts.
Case: A 74-year-old female patient presented to us complaining of gross hematuria.