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Reductive Deuteration of Acyl Chlorides for the Synthesis of ,-Dideuterio Alcohols Using SmI and DO. | LitMetric

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Article Abstract

The synthesis of ,-dideuterio alcohols has been achieved via single electron transfer reductive deuteration of acyl chlorides using SmI and DO. This method is distinguished by its remarkable functional group tolerance and exquisite deuterium incorporation, which has also been applied to the synthesis of valuable deuterated agrochemicals and their building blocks.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9823311PMC
http://dx.doi.org/10.3390/molecules28010416DOI Listing

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