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http://dx.doi.org/10.1038/s41380-022-01915-x | DOI Listing |
J Neurochem
June 2025
Institute of Biomolecular Chemistry, National Research Council, Pozzuoli, Italy.
Circadian light influences brain functions in mammals. Photic non-image-forming stimuli are transduced into electrochemical signals by photosensitive retinal ganglion cells containing melanopsin, a selective blue light-responsive photopigment. The hypothalamus receives light-related information via the retinohypothalamic tract (RHT).
View Article and Find Full Text PDFNat Commun
May 2025
Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY, USA.
Infant care is critical for survival and healthy development. In laboratory mice, unmated males and females display infant-directed behavior ranging from neglect and aggression to alloparental care. Previous research suggests that excitatory neurons in the perifornical area of the hypothalamus (PeFA) mediate pup-directed aggression.
View Article and Find Full Text PDFbioRxiv
January 2025
Department of Cell Biology and Neuroscience, Rowan-Virtua School of Osteopathic Medicine, 42 East Laurel Road, Suite 2200, Stratford, NJ 08084.
Psychosocial stressors are known to promote cocaine craving and relapse in humans but are infrequently employed in preclinical relapse models. Consequently, the underlying neural circuitry by which these stressors drive cocaine seeking has not been thoroughly explored. Using Fos expression analyses, we sought to examine whether the ventromedial hypothalamus (VMH) or periaqueductal gray (PAG), two critical components of the brain's hypothalamic defense system, are activated during psychosocial stress-induced cocaine seeking.
View Article and Find Full Text PDFVitam Horm
January 2025
Clinical Research Center, Murayama Medical Center, Musashimurayama, Japan.
The hypothalamus is the gray matter of the ventral portion of the diencephalon. The hypothalamus is the higher center of the autonomic nervous system and is involved in the regulation of various homeostatic mechanisms. It also modulates respiration by facilitating the respiratory network.
View Article and Find Full Text PDFBiology (Basel)
November 2024
Department of Human Physiology, Faculty of Medicine, University of Málaga, 29010 Malaga, Spain.
The plays a pivotal role in the orchestration of sympathetic nervous system activities. Through its projections to the brainstem and pontomedullary nuclei, it controls heart rate, contractility, blood pressure, and respiratory activity, such as timing and volumes. The DMH integrates inputs from higher brain centers and processes these signals in order to modulate autonomic outflow accordingly.
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