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Background: Imaging assessment for acute ischemic stroke (AIS) patients in the angiosuite using cone beam CT (CBCT) has created increased interest since endovascular treatment became the first line therapy for proximal vessel occlusions. One of the main challenges of CBCT imaging in AIS patients is degraded image quality due to motion artifacts. This study aims to evaluate the prevalence of motion artifacts in CBCT stroke imaging and the effectiveness of a novel motion artifact correction algorithm for image quality improvement.
Methods: Patients presenting with acute stroke symptoms and considered for endovascular treatment were included in the study. CBCT scans were performed using the angiosuite X-ray system. All CBCT scans were post-processed using a motion artifact correction algorithm. Motion artifacts were scored before and after processing using a 4-point scale.
Results: We prospectively included 310 CBCT scans from acute stroke patients. 51% (n=159/310) of scans had motion artifacts, with 24% being moderate to severe. The post-processing algorithm improved motion artifacts in 91% of scans with motion (n=144/159), restoring clinical diagnostic capability in 34%. Overall, 76% of the scans were sufficient for clinical decision-making before correction, which improved to 93% (n=289/310) after post-processing with our algorithm.
Conclusions: Our results demonstrate that CBCT motion artifacts are significantly reduced using a novel post-processing algorithm, which improved brain CBCT image quality and diagnostic assessment for stroke. This is an important step on the road towards a direct-to-angio approach for endovascular thrombectomy (EVT) treatment.
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http://dx.doi.org/10.1136/jnis-2021-018201 | DOI Listing |
Phys Eng Sci Med
September 2025
Department of Radiology, Otaru General Hospital, Otaru, Hokkaido, Japan.
In lung CT imaging, motion artifacts caused by cardiac motion and respiration are common. Recently, CLEAR Motion, a deep learning-based reconstruction method that applies motion correction technology, has been developed. This study aims to quantitatively evaluate the clinical usefulness of CLEAR Motion.
View Article and Find Full Text PDFRadiol Adv
September 2024
Department of Radiology, Northwestern University and Northwestern Medicine, Chicago, IL, 60611, United States.
Background: In clinical practice, digital subtraction angiography (DSA) often suffers from misregistration artifact resulting from voluntary, respiratory, and cardiac motion during acquisition. Most prior efforts to register the background DSA mask to subsequent postcontrast images rely on key point registration using iterative optimization, which has limited real-time application.
Purpose: Leveraging state-of-the-art, unsupervised deep learning, we aim to develop a fast, deformable registration model to substantially reduce DSA misregistration in craniocervical angiography without compromising spatial resolution or introducing new artifacts.
Med Phys
September 2025
Department of Radiology, Stony Brook University, New York, USA.
Background: In contrast-enhanced digital mammography (CEDM) and contrast-enhanced digital breast tomosynthesis (CEDBT), low-energy (LE) and high-energy (HE) images are acquired after injection of iodine contrast agent. Weighted subtraction is then applied to generate dual-energy (DE) images, where normal breast tissues are suppressed, leaving iodinated objects enhanced. Currently, clinical systems employ a dual-shot (DS) method, where LE and HE images are acquired with two separate exposures.
View Article and Find Full Text PDFMed Phys
September 2025
Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong SAR, China.
Background: Four-dimensional magnetic resonance imaging (4D-MRI) holds great promise for precise abdominal radiotherapy guidance. However, current 4D-MRI methods are limited by an inherent trade-off between spatial and temporal resolutions, resulting in compromised image quality characterized by low spatial resolution and significant motion artifacts, hindering clinical implementation. Despite recent advancements, existing methods inadequately exploit redundant frame information and struggle to restore structural details from highly undersampled acquisitions.
View Article and Find Full Text PDFNMR Biomed
October 2025
Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.
Understanding gastric physiology in rodents is critical for advancing preclinical neurogastroenterology research. However, existing techniques are often invasive, terminal, or limited in resolution. This study aims to develop a non-invasive, standardized MRI protocol capable of capturing whole-stomach dynamics in anesthetized rats with high spatiotemporal resolution.
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