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Background: Believing processes represent fundamental brain functions between cognition and emotion. Shortly before the introduction of a compulsory vaccination against COVID-19 in Austria, motives and underlying believing processes regarding the vaccination were collected in individuals with affective disorder (AD) and healthy controls (HC).
Methods: 79 individuals with AD and 173 HC were surveyed online to assess believing processes with the parameters of the credition model (narratives, certainty, emotion, mightiness) about (1) the coronavirus itself and (2) why someone is vaccinated or not. In addition, we calculated congruence scores between content of narrative and type of emotion and divided the narrative content into positive, negative, and indifferent.
Results: There were no differences in vaccination status between AD and HC. Higher levels of certainty were observed in HC compared to AD in both vaccinated and unvaccinated individuals. The effects were higher when asked about the motivation to vaccinate or not than about the coronavirus itself. In HC, more positive emotions and more congruence between emotions and narratives were reported during believing in their vaccination motives. No group differences were found in mightiness for both items. Independently from diagnosis, unvaccinated people had high levels of certainty and more negative emotions and narratives while believing in their motives for not getting vaccinated.
Conclusion: When believing about the COVID-19 vaccination, individuals with AD were more uncertain and experienced fewer positive emotions than HC, although both groups did not differ in vaccination status. These effects were not that strong when believing about the coronavirus in general.
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http://dx.doi.org/10.3389/fpsyg.2022.935278 | DOI Listing |
Anal Chim Acta
November 2025
School of Food and Biological Engineering, Shaanxi University of Science and Technology, Xi'an, 710021, PR China. Electronic address:
Background: Daminozide is a commonly utilized plant growth regulator. Both daminozide and its hydrolysis product, 1,1-dimethyl hydrazine ((CH)NNH), exhibit carcinogenic and teratogenic toxicity. Accurate detection of daminozide in food is of great significance to human health.
View Article and Find Full Text PDFJ Biol Chem
September 2025
Department of Biological Sciences, Ohio University, Athens, Ohio, United States of America; Molecular and Cellular Biology Graduate Program, Ohio University, Athens, Ohio, United States of America. Electronic address:
Temozolomide (TMZ), a DNA alkylator, is a chemotherapeutic agent for brain tumors, but the treatment induces a distinct pattern of mutations, known as a cancer mutational signature SBS11. Although the correlation between TMZ treatment and SBS11 mutations is very clear, the precise biochemical mechanisms that cause SBS11 have not been elucidated. TMZ can alkylate DNA at several locations, among which O-methylguanine (Ome-G) is believed to be most toxic.
View Article and Find Full Text PDFTransplant Cell Ther
September 2025
The Dartmouth Institute for Health Policy & Clinical Practice; Geisel School of Medicine at Dartmouth, Level 5, Williamson Building, One Medical Center Drive, Lebanon, NH, 03756.
Background: The use of patient-reported outcome measures (PROMs) can improve a patient's clinical course by decreasing the incidence and severity of both physical and emotional treatment-related toxicities, uncover unmet patient needs and assist in patients' shared decision-making.
Objectives: The objective of this study was to examine the feasibility and utility of using electronically captured "real time" agenda-setting questions and PROMs at the time of the patient's clinic visit.
Study Design: We designed a prospective observational study that employed a pre-visit questionnaire (PVQ) that included agenda-setting questions and the PROMIS-29 survey, with results incorporated into a clinical decision support dashboard embedded within the patients' electronic medical record (EMR).
PLoS One
September 2025
Department of Communication, Michigan State University, East Lansing, Michigan, United States of America.
Many people who are eligible to participate in the political process do not, suggesting the interests of a large portion of the electorate are not adequately represented in government. While some past work has found that subjective well-being is related to political engagement, less is known about which specific aspects of well-being might drive this effect. We propose and test the idea that self-perceived social contribution - the belief that one's life and everyday activities provide something of value to society - is related to multiple forms of political participation, likely because people who believe they provide something of value to society feel more integrated with society and therefore may be more likely to act on its behalf via political participation.
View Article and Find Full Text PDFChem Sci
August 2025
Siyuan Laboratory, Guangdong Provincial Engineering Technology Research Center of Vacuum Coating Technologies and New Materials, Guangdong Provincial Key Laboratory of Nanophotonic Manipulation, Department of Physics, College of Physics & Optoelectronic Engineering, Jinan University Guangzhou 510632
Sodium (Na) metal batteries (SMBs) are regarded as some of the most promising next-generation energy storage systems due to their high energy density. However, their practical application is severely hindered by interfacial instabilities at both the anode and cathode, which result in rapid capacity degradation during cycling. Here, we proposed a bidirectional interfacial regulation strategy that simultaneously stabilizes both electrode interfaces.
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