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Background: Intraforaminal and extraforaminal nerve root compressions caused by disk herniation or stenosis are relatively common causes of lumbar radiculopathy. Currently, the two available surgical treatment methods are decompression from the spinal canal or lateral decompression via the Wiltse approach.
Objective: To describe a novel transosseous approach to the lumbar nerve root canal.
Methods: Transfacet foraminotomy was performed in 11 patients with intraforaminal or extraforaminal disk herniation. The outcome was measured using the Patient Satisfaction Index (PSI), need for reoperation, radiographic criteria, and finite element analysis.
Results: We noted that at the time of dismissal, PSI scores of 1 and 3 were reported by 10 and one patients, respectively. At the last follow-up, 10 patients reported a PSI score of 1 or 2. Two patients required reoperation because of recurrent disk herniation. Two patients underwent computed tomography (CT) postoperatively, which showed the transfacet approach. Intriguingly, a second postoperative CT after one month showed that the hole through the facet joint had shrunk significantly.
Conclusion: A posterior-anterior transfacet approach for intraforaminal or extraforaminal disk herniations using an ellipsoid facetectomy is safe and allows for fast and comfortable decompression of the nerve root without compromising the long-term strength of the facet joint.
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http://dx.doi.org/10.1080/02688697.2022.2159929 | DOI Listing |
Cureus
August 2025
Department of Neurosurgery, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, BGR.
This report presents the case of a 36-year-old man complaining of chronic low back pain and numbness along the posterolateral surface of the right leg. Magnetic resonance imaging (MRI) revealed a disc degeneration and protrusion at the L-S level and an extensive fluid-equivalent formation with a craniocaudal dimension of 8 cm at the S-S level. Initially, due to the minimal clinical complaints, the cyst was considered asymptomatic.
View Article and Find Full Text PDFBiofabrication
September 2025
Institute of Macromolecular Chemistry, Institute of Macromolecular Chemistry Czech Academy of Sciences, Heyrovského nám. 2, 162 06 Prague 6, Prague, Prague, 162 06, CZECH REPUBLIC.
Extensive peripheral nerve injuries often lead to the loss of neurological function due to slow regeneration and limited recovery over large gaps. Current clinical interventions, such as nerve guidance conduits (NGCs), face challenges in creating biomimetic microenvironments that effectively support nerve repair. The developed GrooveNeuroTube is composed of hyaluronic acid methacrylate and gelatin methacrylate hydrogel, incorporating active agents (growth factors and antibacterial agents) encapsulated within an NGC conduit made of 3D-printed PCL grid fibers.
View Article and Find Full Text PDFNeuron
September 2025
Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China. Electronic address:
Existing treatments for chronic pain often prove ineffective and carry adverse side effects, highlighting the need for better analgesics, including non-pharmacological treatments. We demonstrate that transcutaneous electrical nerve stimulation (TENS), when repeatedly applied during the early phase of nerve injury in mice, produces sustained analgesic effects by activating the dorsal column nucleus (DCN)-thalamic-cortical pathway, which transmits vibration, discriminative touch, and proprioception. Mechanistically, TENS selectively activates glutamatergic neurons in the DCN (DCN) via exciting Aβ low-threshold mechanoreceptors (Aβ-LTMRs) in dorsal root ganglia (DRGs).
View Article and Find Full Text PDFElife
September 2025
Department of Neuroscience, Washington University School of Medicine, St Louis, United States.
Peripheral sensory neurons regenerate their axons after injury to regain function, but this ability declines with age. The mechanisms behind this decline are not fully understood. While excessive production of endothelin 1 (ET-1), a potent vasoconstrictor, is linked to many diseases that increase with age, the role of ET-1 and its receptors in axon regeneration is unknown.
View Article and Find Full Text PDFEur Spine J
September 2025
Faculty of Health, Witten/Herdecke University, Witten, Germany.
Purpose: The aim of this study was to analyze the correlation between volume change in disc herniations and pain improvement after CT guided periradicular therapy.
Methods: Between 5/2017 and 9/2023 46 volumetric MRI examinations of 18 patients suffering from lower back pain were compared to a control group, prior to and following periradicular infiltration therapy. The performed procedure included an image guided application of a glucocorticoid, a local anesthetic and a contrast agent close to the affected nerve root.