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Background: In adhesive small bowel obstructions (ASBOs), literature has shown that passage of a water-soluble contrast challenge at either 8 hours or 24 hours is predictive of successful non-operative management (NOM) for an ASBO, but the long-term outcomes between these two groups are unknown. We hypothesized that patients who require longer transit times to the colon have a higher one-year recidivism of ASBO.
Methods: This was a 4-year review of patients with presumed ASBO undergoing successful NOM. Those requiring operation or those with an SBO due to something other than adhesions were excluded. Patients were divided into two groups (8 hour and 24 hour) based on when contrast reached their right colon. Patients were followed for one year to determine ASBO recurrence.
Results: 137 patients underwent NOM; 112 in the 8-hour group and 25 in the 24-hour group. One-year recurrence rate was 21.4% in the 8-hour group and 40% in the 24-hour group ( = 0.05). The median time to recurrence was 113 days in the 8-hour group and 13 days in the 24-hour group ( = 0.02). Of those who recurred in the 24-hour group, 60% recurred within 30 days ( = 0.01). On univariable analysis, first-time ASBO and 24-hour transit time were risk factors for recurrence.
Conclusions: Adhesive small bowel obstruction patients undergoing NOM in the 24-hour group had a recurrence rate nearly twice that of patients in the 8-hour group and may benefit from an operative exploration during the index hospitalization at the 8-hour mark of a water-soluble contrast challenge, especially if experiencing a first-time ASBO.
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http://dx.doi.org/10.1177/00031348221146973 | DOI Listing |
Drug Des Devel Ther
September 2025
Department of Anesthesiology, Peking University People's Hospital, Beijing, People's Republic of China.
Background: The dopamine D2/D3 antagonist amisulpride has demonstrated its superiority and efficacy in prophylaxis of postoperative nausea and vomiting (PONV). Given the branded intravenous amisulpride (Barhemsys) has not been approved in China, there is unmet clinical need for amisulpride. Our primary objective was to ascertain the efficacy and safety of the generic intravenous amisulpride (QLG2069) in the prophylaxis of PONV.
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View Article and Find Full Text PDFMedicine (Baltimore)
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Department of Geriatrics, Lianyungang Hospital Affiliated to Jiangsu University, Lianyungang, China.
Cerebral small-vessel disease (CSVD) is an important risk factor for cognitive impairment, which is a pressing health issue for the aging population worldwide. The complex relationship between vascular factors, such as blood pressure variability (BPV) and arteriosclerosis index (AI), and cognitive dysfunction in patients with CSVD is a hot research topic, and research in this area will help prevent and treat cognitive dysfunction in CSVD. This study aims to investigate the effects of diastolic BPV (DBPV) and AI on cognitive function in patients with CSVD.
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
Department of Anesthesiology, The First Affiliated Hospital of Traditional Chinese Medicine of Chengdu Medical College, XinDu Hospital of Traditional Chinese Medicine, Chengdu, China.
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Methods: PubMed, Web of Science, Cochrane Library, Embase, and CNKI were searched from inception to October 4, 2022.
J Infect Dev Ctries
August 2025
Teaching Office of Luanzhou Health Vocational School, Tangshan 063004, Hebei Province, China.
Introduction: This study aimed to examine the impact of Epstein-Barr virus (EBV) infection on the occurrence and prognosis of Henoch-Schönlein purpura (HSP).
Methodology: A total of 120 children diagnosed with HSP were selected as the experimental group, and 100 healthy children who underwent physical examinations were the control group. We compared renal function markers and quantified 24-hour urine protein in HSP children with different EBV infection statuses, and analyzed the association between EBV infection and Henoch-Schönlein purpura nephritis (HSPN).