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http://dx.doi.org/10.1210/clinem/dgac730 | DOI Listing |
Insect Sci
September 2025
Department of Entomology & Nematology, University of Florida, Gainesville, Florida.
The sterile insect technique (SIT) is a highly effective biologically-based method for the suppression of many insect pest populations. SIT efficacy could be improved by methods of male sterilization that avoid the use of irradiation that can result in diminished fitness and mating competitiveness. Alternative sterilization methods include conditional disruption of genes for male fertility, or using their sperm-specific promoters to drive the expression of genes for lethal effectors.
View Article and Find Full Text PDFPoult Sci
August 2025
College of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan, 410000, China; Hunan Provincial Engineering Research Center for Safe Poultry Production, Changsha, Hunan 410128, China; Yuelushan Laboratory, Changsha, Hunan 410128, China. Electronic address:
Sexual maturity significantly impacts poultry production efficiency, yet data on testicular development and regulatory mechanisms in indigenous breeds remain limited. In this study, we examined Xianghuang chickens, a indigenous early-maturing breed, to investigate the hypothalamus-pituitary-testis (HPT) axis. Hypothalamus, pituitary, and testis tissues were collected at 80 and 120 days post-hatch (dph) for analysis.
View Article and Find Full Text PDFComp Biochem Physiol B Biochem Mol Biol
September 2025
Jiangsu Key Laboratory of Marine Genetic Resources and Breeding, Jiangsu Ocean University, Lianyungang 222005, China; Co-Innovation Center of Jiangsu Marine Bio-industry Technology, Jiangsu Institute of Marine Resources Development, Lianyungang 222005, China; Jiangsu Key Laboratory of Marine Bioreso
This study investigated the tissue-specific expression and subcellular localization of sex differentiation-related genes of Cyclina sinensis, and then analyzed the effects of hormone treatment (1 and 50 μg/L estradiol treatment (E-1, E-50), 1 and 50 μg/L testosterone (T-1, T-50), and a control group (C)) on the sex ratio, gonadosomatic index, hepatosomatic index, hormone content, and expression of sex differentiation-related genes of juvenile C. sinensis. Vitellogenin (Vg), testis-specific serine kinase 1 (Tssk1), doublesex and mab-3 related transcription factor 1 (Dmrt1), and Wnt family member 4 (Wnt4) were significantly expressed in the gonads of adult C.
View Article and Find Full Text PDFBiogerontology
August 2025
National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi, 110067, India.
Reproductive aging is an emerging global health concern, projected to become the third most significant health issue in the near future, according to the World Health Organization. This complex process is driven by molecular and cellular changes, including alterations in DNA, RNA, and protein expression. Among non-coding RNAs (ncRNAs), long non-coding RNAs (lncRNAs) have been increasingly recognized for their regulatory roles in spermatogenesis and their potential contributions to aging and testicular diseases.
View Article and Find Full Text PDFEvolution
August 2025
Departamento de Genética, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Y chromosomes play important roles in sex determination, male fertility, and, in some cases, hybrid male sterility. Nearly 40 years ago, Zouros and co-workers found that Drosophila mojavensis males carrying a Y chromosome from the sibling species D. arizonae are sterile, with fertility restored by chromosome 4 from D.
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