Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Clinical decision support systems (CDSS) can help identify drug-related problems (DRPs). However, the alert specificity remains variable. Defining more relevant alerts for detecting DRPs would improve CDSS.
Aim: Develop electronic queries that assist pharmacists in conducting medication reviews and an assessment of the performance of this model to detect DRPs.
Method: Electronic queries were set up in CDSS using "triggers" from electronic health records: drug prescriptions, laboratory values, medical problems, vital signs, demographics. They were based on a previous study where 315 patients admitted in internal medicine benefited from a multidisciplinary medication review (gold-standard) to highlight potential DRPs. Electronic queries were retrospectively tested to assess performance in detecting DRPs revealed with gold-standard. For each electronic query, sensitivity, specificity, positive and negative predictive value were computed.
Results: Of 909 DRPs, 700 (77.8%) were used to create 366 electronic queries. Electronic queries correctly detected 77.1% of DRPs, median sensitivity and specificity reached 100.0% (IQRs, 100.0%-100.0%) and 99.7% (IQRs, 97.0%-100.0%); median positive predictive value and negative predictive value reached 50.0% (IQRs, 12.5%-100.0%) and 100.0% (IQRs, 100.0%-100.0%). Performances varied according to "triggers" (p < 0.001, best performance in terms of predictive positive value when exclusively involving drug prescriptions).
Conclusion: Electronic queries based on electronic heath records had high sensitivity and negative predictive value and acceptable specificity and positive predictive value and may contribute to facilitate medication review. Implementing some of these electronic queries (the most effective and clinically relevant) in current practice will allow a better assessment of their impact on the efficiency of the clinical pharmacist.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147748 | PMC |
| http://dx.doi.org/10.1007/s11096-022-01505-5 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Specimen extraction techniques utilized in minimally invasive surgery for uterine cancer and an enlarged uterus: a quality assurance study.
J Robot Surg
September 2025
Department of Gynecologic Oncology, Moffitt Cancer Center, 12902 USF Magnolia Drive, Tampa, FL, 33612, USA.
This study was conducted to investigate the techniques and complications of enlarged uterine extraction during minimally invasive surgery for uterine malignancy. The electronic medical record was queried for patients with uterine malignancy and enlarged uterus (≥ 250 g) who underwent primary hysterectomy with laparoscopic or robotic approach. Statistical analysis was performed using Fisher's exact test for categorical variables and Kruskal-Wallis test for continuous variables.
View Article and Find Full Text PDFCan Communication Skills Be Taught in a Multidisciplinary Maternal Fetal Care Center?
Prenat Diagn
September 2025
Department of Cardiology, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
Objective: To evaluate a structured communication training for providers performing prenatal counseling for patients presenting to a multidisciplinary maternal fetal care center.
Method: Providers who care for pregnant patients with high-risk fetal conditions participated in two half-day virtual training sessions using the VitalTalk methodology. In each session, providers learned the methodology and then participated in role-play with standardized actors.
Comparing physician and artificial intelligence chatbot responses to posthysterectomy questions posted to a public social media forum.
AJOG Glob Rep
August 2025
Department of Obstetrics, Gynecology & Women's Health, University of Hawaii, Honolulu, HI (Kho).
Background: Within public online forums, patients often seek reassurance and guidance from the community regarding postoperative symptoms and expectations, and when to seek medical assistance. Others are using artificial intelligence in the form of online search engines or chatbots such as ChatGPT or Perplexity. Artificial intelligence chatbot assistants have been growing in popularity; however, clinicians may be hesitant to use them because of concerns about accuracy.
View Article and Find Full Text PDFAdults With Congenital Heart Disease Have an Increased Prevalence of Autoimmunity.
JACC Adv
September 2025
Section of Cardiovascular Medicine, Departments of Pediatrics and Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA. Electronic address:
Background: Adult congenital heart disease (ACHD) individuals have increased risk of noncardiac comorbidities including cancer and infections. Whether they are at increased risk of autoimmunity is unknown.
Objectives: The purpose of this study was to understand the association of ACHD and risk for autoimmunity.
Outpatient and Inpatient Management of Infants and Children With Eczema Herpeticum Diagnosed in the Emergency Department.
Pediatr Dermatol
September 2025
Department of Pediatrics, University of Hawaii John A. Burns School of Medicine, Honolulu, Hawaii, USA.
Background: There are no universally established guidelines for when pediatric EH warrants hospitalization or intravenous (IV) acyclovir over oral therapy. To address this lack of consensus, this study aimed to describe outcomes of outpatient oral acyclovir treatment in pediatric EH cases, including rates of disease exacerbation, hospitalizations, and complications.
Methods: We conducted a retrospective cohort review of pediatric patients under age 7 diagnosed with EH who presented to the pediatric emergency department (ED) between January 1, 2008, and December 31, 2022.