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Objectives: Abdominal obesity favors the involvement of cardiometabolic complications in renal patients on hemodialysis. Thus, the aim of the study was to identify the cut-points of the conicity index in individuals undergoing hemodialysis.
Methods: This was a cross-sectional study carried out with 953 individuals undergoing hemodialysis in clinics in a metropolitan region of southeastern Brazil. The conicity index was calculated using the following mathematical equation: waist circumference/0.109 × √weight/height. The receiver operating characteristic (ROC) curve was calculated from the analysis of latent classes by cross-validation through a latent variable of abdominal obesity. This latent variable was defined using the response pattern of the observed anthropometric variables considering the presence and absence of abdominal obesity: waist circumference, waist-to-height ratio, and body shape index. The cut-points identified were elucidated by the area under the curve (AUC), Youden index, sensitivity, and specificity.
Results: The cut-points for the conicity index found for both sexes were similar, resulting in a cut-point for men of 1.275 (AUC, 0.921; Youden index, 0.666), with a sensitivity and specificity of 83% and 83.6%, and a cut-point for women of 1.285 (AUC, 0.921; Youden index, 0.679), with a sensitivity and specificity of 78.6% and 89.3%, respectively.
Conclusions: The conicity index showed high discriminatory power for the identification of abdominal obesity in hemodialysis patients, therefore it can be a simple and easily accessible tool to be incorporated into clinical practice in this population.
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http://dx.doi.org/10.1016/j.nut.2022.111890 | DOI Listing |
Abdom Radiol (NY)
September 2025
Research Centre for Optimal Health, School of Life Sciences, University of Westminster, London, UK.
Objectives: The escalating global incidence of obesity, cardiometabolic disease and sarcopenia necessitates reliable body composition measurement tools. MRI-based assessment is the gold standard, with utility in both clinical and drug trial settings. This study aims to validate a new automated volumetric MRI method by comparing with manual ground truth, prior volumetric measurements, and against a new method for semi-automated single-slice area measurements.
View Article and Find Full Text PDFJ Obes
September 2025
School of Natural Sciences, University of Lincoln, Lincoln, UK.
To investigate the genetic determinants of fat distribution across anatomical sites and their implications for health outcomes. We analyzed neck-to-knee MRI data from the UK Biobank ( = 37,589) to measure fat at various locations and used Mendelian randomization to assess effects on 26 obesity-related diseases and 94 biomarkers from FinnGen and other consortia. We identified genetic loci associated with 10 fat depots: abdominal subcutaneous adipose tissue ( = 2 loci), thigh subcutaneous adipose tissue (25), thigh intermuscular adipose tissue (15), visceral adipose tissue (7), liver proton density fat fraction (PDFF) (8), pancreas PDFF (11), paraspinal adipose tissue (9), pelvic bone marrow fat (28), thigh bone marrow fat (27), and vertebrae bone marrow fat (5).
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
The Third Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.
Background: Multiple non-pharmacological and nonsurgical interventions have demonstrated efficacy in improving abdominal obesity. However, the optimal intervention remains uncertain. This study aimed to assess the relative effectiveness and safety of these interventions in reducing waist circumference, waist-to-hip ratio, waist-to-height ratio (WHtR), body mass index (BMI), and body weight among adults with abdominal obesity.
View Article and Find Full Text PDFBMC Oral Health
September 2025
Department of Oral Medicine and Periodontology, Ain Shams University, Cairo, Egypt.
Background: Periodontitis, a chronic inflammatory disease of tooth-supporting tissues, shows significant associations with systemic conditions like type 2 diabetes mellitus (T2DM) and obesity. These metabolic disorders share chronic inflammatory pathways that may influence periodontal disease severity. This study investigated these relationships using advanced quantifiable metrics - periodontal epithelial surface area (PESA) and periodontal inflammatory surface area (PISA).
View Article and Find Full Text PDFAm J Health Promot
September 2025
Facultad de Ciencias de la Salud, Universidad Autónoma de Tlaxcala, Tlaxcala, México.
PurposeTo assess the effectiveness of a school-based intervention to promote healthy behaviors and prevent weight gain in children.DesignCluster randomized trial.SettingSeven elementary schools from Mexico.
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