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The COVID-19 pandemic has highlighted the adverse health, economic and social consequences of longstanding social inequality on various communities, groups, and individuals. Because they lack sufficient access to health and social resources, vulnerable groups affected by lower incomes, geographic remoteness, and/or low awareness of disease prevention and control measures are more susceptible to infection (McDonald, 2022; Mein, 2020; Moghanibashi-Mansourieh, 2021). According to The Lancet (2020) editorial board, vulnerable groups are defined as segments of the population disproportionately exposed to risk. People not considered vulnerable at the start of the pandemic may become vulnerable afterward due to pandemic-related effects such as loss of income and lack of access to social support. Thus, during the COVID-19 pandemic, vulnerable groups include not only traditionally vulnerable populations (e.g., older adults, infants, immuno-compromised individuals) but socioeconomic groups that may be financially, mentally, or physically struggling to cope. In addition, schools of all levels around the world have adopted remote online synchronous or asynchronous teaching methods to avoid pandemic-related school closures and interruptions in student learning (Dreesen et al., 2020). However, issues such as the accessibility, availability, acceptability, and applicability of online learning equipment for vulnerable students should be comprehensively considered by the government. Governments encounter multiple challenges related to the above-mentioned issues, including (1) dealing with the public health effects of the pandemic crisis; (2) dealing with related economic and social impacts such as social and economic depression due to isolation, tax reductions, increased payments, subsidies, compensation, and the provision of unemployment insurance (Moghanibashi-Mansourieh, 2021); and (3) reforming education teaching methods and providing appropriate information and equipment of vulnerable groups. In responding to COVID-19, policymakers should consider the risks of exacerbating the inequalities faced by vulnerable groups. Moreover, vulnerable groups should be clearly identified to limit the long-term consequences of the pandemic. Governments must continually identify vulnerable / at-risk populations and provide equitable support to those most at risk.
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http://dx.doi.org/10.6224/JN.202212_69(6).01 | DOI Listing |
Mol Biol Rep
September 2025
School of Arts and Sciences, Department of Natural and Applied Sciences, The American University of Iraq-Baghdad, Baghdad, Iraq.
The COVID-19 pandemic, caused by the continuously evolving SARS-CoV-2 virus, has presented persistent global health challenges. As novel variants emerge, many with enhanced transmissibility and immune evasion capabilities, concerns have intensified regarding the efficacy of existing vaccines and therapeutics. This review provides a comprehensive overview of the current landscape of COVID-19 vaccination, including the development and performance of monovalent and bivalent boosters, and examines their effectiveness against newly emerging variants of interest (VOIs) and variants under monitoring (VUMs), such as JN.
View Article and Find Full Text PDFIISE Trans Occup Ergon Hum Factors
September 2025
Department of Industrial and Systems Engineering, Virginia Tech, Blacksburg, Virginia, USA.
Occupational ApplicationsWe investigated the effects of age and sex on cybersickness susceptibility during Virtual Reality (VR)-based forklift training, using an order picker forklift truck consisting of basic and common forklift driving scenarios. Cybersickness occurrence was assessed using the Simulator Sickness Questionnaire (SSQ) and analyzed with the survival analysis method. Our analysis indicated strong vulnerability among older adults yet no significant influence of biological sex on cybersickness susceptibility.
View Article and Find Full Text PDFInt J Surg
September 2025
Department of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Background: Phrenic nerve injury during mediastinal tumor resection can lead to significant postoperative diaphragmatic dysfunction. Current intraoperative protection techniques are imprecise and lack real-time feedback. We aimed to develop and validate a quantifiable, multimodal neuroprotective strategy.
View Article and Find Full Text PDFJ Magn Reson Imaging
September 2025
Department of Radiology, Huashan Hospital, Fudan University, Shanghai, China.
Background: Parkinson's disease (PD) often presents with lateralized motor symptoms at onset, reflecting asymmetric degeneration of the substantia nigra (SN). Neuromelanin (NM) loss and iron accumulation are hallmarks of SN pathology in PD, but their spatial distribution and interrelationship in PD patients with right-sided (PDR) or left-sided (PDL) motor symptom onset remain unclear.
Purpose: To investigate the spatial vulnerability and interrelationship of NM and iron in the SN among PDR, PDL, and healthy controls (HCs) using MRI.
J Pediatric Infect Dis Soc
September 2025
Infectious Diseases Unit, 3rd Department of Pediatrics, Aristotle University School of Medicine, Hippokration Hospital, Thessaloniki, Greece.
Background: Critically ill pediatric patients admitted to the PICU are highly vulnerable to infections, including invasive fungal diseases and antifungal agents are frequently prescribed. Little is known about antifungal usage in PICUs across Europe.
Methods: A multinational 3-month weekly point-prevalence study for measuring antifungal drug use was organized.