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Aim: To examine the relationship between the number of present and functional teeth at baseline and future incidence of loss of independence.
Methods: Participants were community-dwelling older individuals who participated in a comprehensive geriatric health examination conducted in Kusatsu town, Japan, between 2009 and 2015. The primary endpoint was the incidence of loss of independence among participants, defined as the first certification of long-term care insurance in Japan. The numbers of present and functional teeth at baseline were determined via an oral examination. Demographics, clinical variables (e.g., history of chronic diseases and psychosocial factors), blood nutritional markers, physical functions, and perceived masticatory function were assessed.
Results: This study included 1121 individuals, and 205 individuals suffered from loss of independence during the follow-up period. Kaplan-Meier estimates of loss of independence for participants with smaller numbers of present and functional teeth were significantly greater than for those with larger numbers of teeth. Cox proportional hazard analyses indicated that a smaller number of present teeth was not a significant risk factor after adjusting for demographic characteristics. However, the number of functional teeth was a significant risk factor after the adjustment (hazard ratio: 1.975 [1.168-3.340]). Additionally, higher hazard ratios were observed in other adjusted models, but they were not statistically significant.
Conclusions: The number of functional teeth may be more closely related to the future incidence of loss of independence than the number of present teeth. This novel finding suggests that prosthodontic rehabilitation for tooth loss possibly prevents the future incidence of this life-event. Geriatr Gerontol Int 2022; 22: 1032-1039.
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http://dx.doi.org/10.1111/ggi.14508 | DOI Listing |
J Adv Prosthodont
August 2025
Department of Prosthodontics, Istanbul University, Istanbul, Turkey.
Purpose: This study investigated how different data collection methods affect final restoration design and dynamic occlusal morphology.
Materials And Methods: Digital systems allow intraoral recording of functional occlusal paths through the digitally recorded functionally generated pathway (DRFGP) technique, using intraoral scanners and optical jaw tracking. Two substudies were conducted.
Front Aging Neurosci
August 2025
Department of Prosthodontics, Beijing Stomatological Hospital, School of Stomatology, Capital Medical University, Beijing, China.
Introduction: Alzheimer's Disease (AD) is a common neurodegenerative disease among the elderly population. It has been posited that the onset and progression of AD are influenced by a combination of various factors. Occlusal support loss due to tooth loss has been reported to be a risk factor triggering cognitive dysfunction.
View Article and Find Full Text PDFIEEE Trans Autom Sci Eng
January 2025
H. Milton Stewart School of Industrial and Systems Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Cone beam computed tomography (CBCT) is a widely-used imaging modality in dental healthcare. It is an important task to segment each 3D CBCT image, which involves labeling lesions, bone, teeth, and restorative material on a voxel-by-voxel basis, as it aids in lesion detection, diagnosis, and treatment planning. The current clinical practice relies on manual segmentation, which is labor-intensive and demands considerable expertise.
View Article and Find Full Text PDFNan Fang Yi Ke Da Xue Xue Bao
August 2025
Department of Encephalopathy, First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou 450000, China.
Objectives: To exple the mechanism of Granules (QXZG) for enhancing synaptic plasticity in aging rats.
Methods: Forty SD rats were randomized into control group, aging model group, donepezil treatment group, and QXZG treatment group (=10). Except for the control rats, all the rats were subjected to daily intraperitoneal injection of D-galactose for 8 consecutive weeks to induce brain aging, and donepezil hydrochloride and QXZG suspension were administered by gavage during modeling.
Int Endod J
September 2025
Department of Biochemistry, School of Dentistry, IHBR, Kyungpook National University, Daegu, South Korea.
Aim: Prickle planar cell polarity (PCP) protein 2 (Prickle2) encodes a homologue of Drosophila prickle and is involved in the non-canonical Wnt/PCP signalling pathway. However, its exact role in dentinogenesis remains unclear. Dentinogenesis, a key process in tooth morphogenesis, involves the patterned arrangement of odontoblasts and the formation of dentine matrix along the pulp cavity.
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