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Transcatheter pacing systems are self-contained, leadless, devices that offer the potential benefits of avoiding complications related to pectoral pocket and upper extremity vascular access. These systems in preapproval trials demonstrated excellent safety profile with the incidence of device-related cardiac perforation as low as 1.6% with Micra™ (Medtronic) and 1.3% in Nanostim (Abbott). In post-approval registry of Micra™ TPS, the rate of major complications was even lower than in the investigational study ranging from 0.63% to 0.77%. Recently, published report found much higher rates of need for rescue surgery, shock, tamponade, and death among patients implanted with the Micra™ device when compared with transvenous devices. This case report describes two cases of major right ventricular perforation requiring surgical intervention.
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http://dx.doi.org/10.1002/hsr2.869 | DOI Listing |
Science
September 2025
Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Ventricular tachycardia disrupts the heart's coordinated pump function, leading to sudden cardiac death. Neutrophils, which are recruited in high numbers to the ischemic myocardium, promote these arrhythmias. Comparing neutrophils with macrophages, we found that resistin-like molecule γ ( or RELMγ) was the most differentially expressed gene in mouse infarcts.
View Article and Find Full Text PDFJ Cardiovasc Electrophysiol
August 2025
Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Am J Cardiol
August 2025
Department of Ultrasound, The First Affiliated Hospital of Yangtze University,Jianghan Road, Jingzhou,Hubei Province, China. Electronic address:
None.
View Article and Find Full Text PDFInterdiscip Cardiovasc Thorac Surg
September 2025
Division of Cardiovascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Objectives: Anomalous papillary muscles (PMs) directly inserted into the anterior mitral valve (MV) constitute an infrequent anomaly in obstructive hypertrophic cardiomyopathy (HCM). This study sought to evaluate the efficacy and safety of a novel approach with transapical beating-heart septal myectomy to relieve obstruction while avoiding abnormal PM manipulation.
Methods: Among 439 patients with obstructive HCM from March 2023 to February 2024, 27 patients (6.
Pediatr Cardiol
August 2025
The Heart Institute, Children's Hospital Colorado, Aurora, CO, USA.
The use of augmented reality (AR) for pre-procedural planning has increased over the past decade, yet its real-time application during complex cardiac interventions remains novel. This case highlights the integration of AR technology during a challenging transcatheter pulmonary valve replacement (TPVR) using a self-expanding system in a pediatric patient. A 12-year-old male with a history of congenital pulmonary valve stenosis presented with progressive right ventricular dilation and exercise intolerance.
View Article and Find Full Text PDF