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Objective: Chronic otitis media (COM) can seriously impact quality of life (QOL). Disease-specific questionnaires are essential for an accurate assessment of this impact. There is no questionnaire available for French-speaking patients with COM. This study aims to adapt and validate the French version of the COMQ-12 questionnaire.
Design: This is a controlled, prospective study, conducted between May 2020 and December 2021. Translation was performed using a forward-backward technique, and statistical validation was performed with a COM patients and a controls adult cohorts.
Study Sample: 100 patients (mean age 48 ± 16), and 50 controls (mean age 41 ± 16; = 0.02) completed the test.
Results: Internal consistency, assessed by Cronbach's alpha, was 0.870 for the cases group. The mean COMQ-12 total score was 23.92 ± 11.3 for cases versus 3.70 ± 6.15 for controls ( < 0.0001). Individual items all had high discriminatory performances. The three items concerning ear discharge (Q1, Q2, Q9) had weaker correlation with the other items and the global score, but did not have a negative impact on internal consistency.
Conclusion: The French version of the COMQ-12 is a short and easy-to-use test, with robust statistical properties, for assessing QOL in patients with COM.
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http://dx.doi.org/10.1080/14992027.2022.2140314 | DOI Listing |
Lemierre's syndrome (LS), otherwise known as postanginal sepsis, is a frequently overlooked condition characterized by septic thrombophlebitis of the internal jugular vein (IJV), usually caused by oropharyngeal infection. However, ear space (otogenic) infections are one of the atypical causes of LS and have been rarely reported. We present a case of a male in his 20s with a history of recurrent acute otitis media (RAOM) who presented with purulent ear discharge, fever, neck pain, and swelling for a week.
View Article and Find Full Text PDFMol Genet Genomics
September 2025
Department of Biochemistry, Bahauddin Zakariya University, Multan, Multan, 66000, Punjab, Pakistan.
Moraxella catarrhalis is a Gram-negative diplococcus bacterium and a common respiratory pathogen, implicated in 15-20% of otitis media (OM) cases in children and chronic obstructive pulmonary disease (COPD) in adults. The rise of drug-resistant Moraxella catarrhalis has highlighted the urgent need for the potent vaccine strategies to reduce its clinical burden. Despite a mortality rate of 13%, there is no FDA-approved vaccine for this pathogen.
View Article and Find Full Text PDFAuris Nasus Larynx
September 2025
Department of Otolaryngology, Deafness and Middle Ear Surgicenter Tokyo Kita Medical Center, 4-17-56 Akabanedai, Kita-ku, Tokyo 115-0053, Japan; Department of Otolaryngology, Head and Neck Surgery, Jichi University Saitama Medical Center, 1-847 Amanuma-cho, Omiya-ku, Saitama 330-0834, Japan.
Objective: This study aimed to evaluate the effect of age at tympanostomy tube insertion on mastoid air cell development, focusing on whether insertion before 3 years of age is associated with more favorable pneumatization.
Methods: We retrospectively analyzed 39 children (71 ears) who developed tympanic membrane perforation following tube insertion (tube group), including cases primarily associated with recurrent acute otitis media (rAOM) and otitis media with effusion (OME). The control group consisted of 41 children (41 ears) with congenital cholesteatoma, using their contralateral normal ears as controls.
World J Radiol
August 2025
Department of Radiology, Faculty of Medicine, Erzincan Binali Yildirim University, Erzincan 24000, Basbaglar, Türkiye.
Chronic otitis media (COM) is a long-standing inflammatory condition affecting the middle ear and mastoid cavity, often resulting in progressive structural damage and functional deficits. Radiological imaging is fundamental in diagnosing the disease, assessing its severity, and identifying possible complications. The literature indicates that the prevalence rates of extracranial and intracranial complications range from 0.
View Article and Find Full Text PDFFront Cell Infect Microbiol
September 2025
Department of Otolaryngology, The Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Introduction: The gut microbiota derived metabolites show significant therapeutic effects on otitis media, yet the specific active metabolites and mechanisms involved remain undocumented. The primary objective of the study was to utilise a network pharmacology approach to investigate the active metabolites and underlying mechanisms by which gut microbiota exerts their effects against otitis media.
Methods: A set of 110 gut microbiota-derived metabolites was retrieved from the MiMeDB database.