Increased comfortable gait speed is associated with improved gait biomechanics in persons with Parkinson's disease completing an 8-week aerobic cycling intervention.

Parkinsonism Relat Disord

Cleveland Clinic, Department of Biomedical Engineering, 9500 Euclid Avenue, Cleveland, OH, 44195, USA; Cleveland Clinic, Concussion Center, 9500 Euclid Avenue, Cleveland, OH, 44195, USA; Cleveland Clinic, Center for Neurologic Restoration, 9500 Euclid Avenue, Cleveland, OH, 44195, USA. Electronic ad

Published: November 2022


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.parkreldis.2022.10.010DOI Listing

Publication Analysis

Top Keywords

increased comfortable
4
comfortable gait
4
gait speed
4
speed associated
4
associated improved
4
improved gait
4
gait biomechanics
4
biomechanics persons
4
persons parkinson's
4
parkinson's disease
4

Similar Publications

Thermal microclimate assessment in dairy cow milking parlors: Seasonal variations in temperature-humidity index and implications for heat stress.

Vet World

July 2025

Department of Animal Husbandry, Ruminant Animals and Animal Products Technologies, Faculty of Agriculture, Trakia University, 6000, Bulgaria.

Background And Aim: Rising global temperatures and increasing humidity levels are intensifying the risk of heat stress (HS) in high-yielding dairy cattle. The temperature-humidity index (THI) is a standard metric for evaluating thermal stress in livestock. This study aimed to assess seasonal and diurnal variations in temperature, relative humidity, and THI within a milking parlor and determine their compliance with established thermal comfort thresholds for dairy cows.

View Article and Find Full Text PDF

Background: Parkinson's disease (PD) is characterized by motor symptoms altering gait domains such as slow walking speed, reduced step and stride length, and increased double support time. Gait disturbances occur in the early, mild to moderate, and advanced stages of the disease in both backward walking (BW) and forward walking (FW), but are more pronounced in BW. At this point, however, no information is available about BW performance and disease stages specified using the Hoehn and Yahr (H&Y) scale.

View Article and Find Full Text PDF

A numerical investigation of the kinematic and fluid dynamic behaviour of an intramuscular autoinjector designed for optimising injection efficiency.

Med Eng Phys

October 2025

Department of Mechanical Engineering, University of Cape Town, 7701, South Africa; Centre for Research in Computational and Applied Mechanics (CERECAM), University of Cape Town, 7701, South Africa.

The usability and versatility of autoinjectors in managing chronic and autoimmune diseases have made them increasingly attractive in medicine. However, investigations into autoinjector designs require an understanding of the kinematic properties and fluid behaviour during injection. To optimise injection efficiency, this study develops a mathematical and computational fluid dynamics (CFD) model of an IM autoinjector by investigating the effects of viscosity, needle length, needle diameter, and medication volume on the injection process.

View Article and Find Full Text PDF

The Analgesia Nociception Index (ANI) has been used to assess discomfort in anesthetized adults. The COMFORT Behavior Scale (CBS) is recommended for assessing discomfort in intubated and sedated children. The primary objective of the present study was to assess the validity and performance of the ANI as an indicator of discomfort in intubated, ventilated children in a pediatric intensive care unit (PICU).

View Article and Find Full Text PDF

Postoperative shivering is a common complication following anesthesia, which can increase oxygen consumption, prolong recovery, and affect patient comfort and safety. Understanding its risk factors is important for improving postoperative outcomes and guiding preventive strategies. To investigate the associated risk factors for postoperative shivering after total knee arthroplasty (TKA) and to develop and validate a predictive model.

View Article and Find Full Text PDF