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http://dx.doi.org/10.1016/j.parkreldis.2022.10.010 | DOI Listing |
Vet World
July 2025
Department of Animal Husbandry, Ruminant Animals and Animal Products Technologies, Faculty of Agriculture, Trakia University, 6000, Bulgaria.
Background And Aim: Rising global temperatures and increasing humidity levels are intensifying the risk of heat stress (HS) in high-yielding dairy cattle. The temperature-humidity index (THI) is a standard metric for evaluating thermal stress in livestock. This study aimed to assess seasonal and diurnal variations in temperature, relative humidity, and THI within a milking parlor and determine their compliance with established thermal comfort thresholds for dairy cows.
View Article and Find Full Text PDFBMC Neurol
September 2025
Department of Neurology, University Hospital Schleswig-Holstein, Kiel, Germany.
Background: Parkinson's disease (PD) is characterized by motor symptoms altering gait domains such as slow walking speed, reduced step and stride length, and increased double support time. Gait disturbances occur in the early, mild to moderate, and advanced stages of the disease in both backward walking (BW) and forward walking (FW), but are more pronounced in BW. At this point, however, no information is available about BW performance and disease stages specified using the Hoehn and Yahr (H&Y) scale.
View Article and Find Full Text PDFMed Eng Phys
October 2025
Department of Mechanical Engineering, University of Cape Town, 7701, South Africa; Centre for Research in Computational and Applied Mechanics (CERECAM), University of Cape Town, 7701, South Africa.
The usability and versatility of autoinjectors in managing chronic and autoimmune diseases have made them increasingly attractive in medicine. However, investigations into autoinjector designs require an understanding of the kinematic properties and fluid behaviour during injection. To optimise injection efficiency, this study develops a mathematical and computational fluid dynamics (CFD) model of an IM autoinjector by investigating the effects of viscosity, needle length, needle diameter, and medication volume on the injection process.
View Article and Find Full Text PDFJ Clin Monit Comput
September 2025
Pediatric Intensive Care Unit, CHU Lille, 59000, Lille, France.
The Analgesia Nociception Index (ANI) has been used to assess discomfort in anesthetized adults. The COMFORT Behavior Scale (CBS) is recommended for assessing discomfort in intubated and sedated children. The primary objective of the present study was to assess the validity and performance of the ANI as an indicator of discomfort in intubated, ventilated children in a pediatric intensive care unit (PICU).
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
Sichuan Orthopedic Hospital, Ya'an, China.
Postoperative shivering is a common complication following anesthesia, which can increase oxygen consumption, prolong recovery, and affect patient comfort and safety. Understanding its risk factors is important for improving postoperative outcomes and guiding preventive strategies. To investigate the associated risk factors for postoperative shivering after total knee arthroplasty (TKA) and to develop and validate a predictive model.
View Article and Find Full Text PDF