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The Mediterranean Diet plays a critical role in the prevention of primary cardiovascular disease (CVD). Actually, there is a scarcity of evidence for secondary prevention. The current study aims to assess adherence to the Mediterranean diet (MD) in patients recently admitted to the Cardiac Rehabilitation Unit following acute cardiovascular disease. Adherence to MD was assessed in 111 patients admitted to the Cardiac Rehabilitation Unit of the Federico II Hospital in Naples. The Medi-Lite score was used to assess adherence to MD. The main determinant of reduced MD compliance was assessed using Pearson's correlation analysis and a multivariable regression model. The population had a median MD adherence score of 11 and a mean score of 10.9. The lowest possible score was 5 (indicating poor adherence), and the highest possible score was 15 (excellent adherence index). There were 3 participants with a poor score (<7), 82 with a good score (7-12), and 26 with an excellent score (³13). Lower Medi-Lite score was associated with younger age and being an active worker in a multivariate regression model (both p<0.05). Our findings show that among patients admitted to the Cardiac Rehabilitation Unit after a major CV event, young active workers have the lowest adherence to MD, requiring an individualized and multidisciplinary approach to improve their adherence to MD for secondary CV prevention.
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http://dx.doi.org/10.4081/monaldi.2022.2391 | DOI Listing |
BMC Microbiol
September 2025
Faculty of Kinesiology, University of Calgary, Calgary, AB, Canada.
Background: A plant-focused, healthy dietary pattern, such as the Mediterranean diet enriched with dietary fiber, polyphenols, and polyunsaturated fats, is well known to positively influence the gut microbiota. Conversely, a processed diet high in saturated fats and sugars negatively impacts gut diversity, potentially leading to weight gain, insulin resistance, and chronic, low-grade inflammation. Despite this understanding, the mechanisms by which the Mediterranean diet impacts the gut microbiota and its associated health benefits remain unclear.
View Article and Find Full Text PDFHipertens Riesgo Vasc
September 2025
Grupo de Obesidad y Síndrome Metabólico, Asociación Española de Especialistas en Medicina del Trabajo (AEEMT), Spain; Grupo ADEMA-Salud, IUNICS Universidad de las Islas Baleares, Palma de Mallorca, Spain.
Introduction And Objectives: Obesity has been considered the pandemic of the 21st century due to its high prevalence and the significant morbidity and mortality it entails. The aim of this study is to assess the prevalence of obesity in two occupational sectors and to determine the variables associated with it.
Methodology: This is a cross-sectional and descriptive study involving 56,856 workers from the commerce and industrial sectors.
Semin Arthritis Rheum
August 2025
Division of Rheumatology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA; Department of Quantitative Health Sciences, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA. Electronic address:
Objectives: We aimed to determine the degree to which a healthy dietary pattern is associated with incident rheumatoid arthritis (RA).
Methods: We registered this systematic review and meta-analysis in PROSPERO (CRD42025645056). Inclusion criteria were validated diet (anti-inflammatory, Mediterranean, Dietary Approaches to Stop Hypertension (DASH), and/or healthy eating index [HEI]); validated RA definition; dietary exposure preceding RA; and randomized controlled trial, cohort, or case-control design.
Mol Nutr Food Res
September 2025
Department of Clinical Medicine and Surgery, Physiology Unit, University of Naples "Federico II", Napoli, Italy.
This study evaluated the effect of a nutraceutical supplementation (NS) and Mediterranean hypocaloric diet (MHD) on hepatic steatosis indices (HSIs), γ-glutamyl transferase (γGT), and lipid profile in adults with hyperlipidemia and nonalcoholic fatty liver disease (NAFLD). In vitro study on HepG2 cells explored potential molecular mechanisms. A retrospective study was conducted on 45 overweight/obese subjects (19 M) prescribed MHD with/without NS.
View Article and Find Full Text PDFInt Immunopharmacol
September 2025
Amity Institute of Pharmacy, Amity University Kolkata, Major Arterial Road, Action Area II, Newtown, Kolkata 700135, West Bengal, India. Electronic address:
Diabetes mellitus (DM) and multiple sclerosis (MS), while affecting metabolic and neurological systems respectively, share convergent immunometabolic pathways. This review synthesizes recent evidence elucidating overlapping mechanisms linking DM and MS, emphasizing metabolic dysfunction and systemic inflammation, with therapeutic potential of lifestyle interventions alongside pharmacotherapy. A comprehensive literature analysis examined shared pathogenesis through recent studies.
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