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http://dx.doi.org/10.1161/CIRCRESAHA.122.321556 | DOI Listing |
J Therm Biol
September 2025
Hainan Key Laboratory of Tropical Animal Reproduction & Breeding and Epidemic Disease Research, School of Tropical Agriculture and Forestry, Hainan University, Haikou, 570228, China. Electronic address:
In light of the challenges posed by global climate change, the environmental adaptability of organisms is becoming increasingly important. The Wuzhishan (WZS) pig, tolerant to high heat and humidity, is an ideal model for genomic study. By characterizing its genome and assessing its genetic diversity and runs of homozygosity (ROH), we can gain insights into its current conservation status and genomic architecture.
View Article and Find Full Text PDFPostgrad Med J
September 2025
Department of Basic Medicine, Shantou University Medical College, 22 Xinling Road, Jinping District, Shantou, Guangdong, 515041, China.
Background: Coronary atherosclerosis is a leading cause of cardiovascular disease and death worldwide. Despite progress in understanding its pathogenesis, the roles of circulating inflammatory proteins and plasma metabolites are complex and not fully elucidated. Existing Mendelian randomization (MR) studies often target isolated biomarkers, lacking comprehensive and mechanistic insights.
View Article and Find Full Text PDFMed Sci (Paris)
September 2025
UMI233 TransVIHMI (Recherches translationnelles sur le VIH et les maladies infectieuses), Université de Montpellier, IRD, INSERM Unité 1175, Montpellier, France.
For a long time neglected, the mpox virus has caused two public health emergency declarations by the World Health Organization in just two years. Rapid detection and characterization of the viral strains involved are crucial for better control of the disease. Recent work on viral genome sequencing in the Democratic Republic of the Congo (DRC) has shown the emergence in 2023 of clade Ib, with sustained human-to-human transmission and rapid spread to several other non-endemic neighboring countries, as well as outside Africa.
View Article and Find Full Text PDFGenes (Basel)
August 2025
Medical Faculty, Department of Medical Genetics, Medical University of Sofia, Sofia 1000, Bulgaria.
The journal retracts the article "Pathogenic Variants Associated with Rare Monogenic Diseases Established in Ancient Neanderthal and Denisovan Genome-Wide Data" [...
View Article and Find Full Text PDFCirculation
September 2025
Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany (J.K., L.S., K.F., L.M.S.).