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This case report presents a 72-year-old man with longstanding recurrent respiratory papillomatosis (RRP). He has undergone multiple procedures for the condition, including an apparent urgent surgical airway followed by tracheoplasty repair. Modern management of complicated RRP should include both local debulking and systemic approaches. Systemic bevacizumab (Avastin) has shown some initial success as an effective treatment option, in addition to other medications such as pembrolizumab. Other future care strategies may include an HPV vaccination and other adjuvants; vaccination has been reported to have the possibility of drastically reducing the incidence of RRP.
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http://dx.doi.org/10.1177/01455613221128714 | DOI Listing |
Background: Recurrent laryngeal nerve palsy (RLNP) is not uncommon after thyroid surgery and can be debilitating. This is a retrospective cohort analysis of outcomes in patients with RLNP post-thyroidectomy for differentiated thyroid malignancy.
Method: Clinicopathological details as well as outcomes of thyroidectomies for differentiated thyroid cancer in 862 patients performed over a period of 22 years (2001-2023) for nerve palsy were collected.
Laryngoscope
August 2025
National Centre for Airway Reconstruction, Imperial College Healthcare NHS Trust, London, UK.
Objective: Full-thickness resection and skin grafting of the laryngotracheal junction, the "Maddern Procedure," can be used to treat patients with recalcitrant laryngotracheal stenosis. We report the long-term surgical outcomes of this procedure.
Methods: A consecutive series of 27 females with idiopathic, iatrogenic, or vasculitic subglottic stenosis who underwent the Maddern procedure between 2012 and 2023 were retrospectively reviewed.
Reumatismo
July 2025
Rheumatology Unit, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo.
Laryngotracheal granulomatous inflammation is a clinical entity that may complicate either localized or systemic disorders. It can result in life-threatening airway compromise, requiring urgent medical or surgical intervention. We report the case of a patient presenting with recurrent tracheal stenosis secondary to anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis, refractory to conventional treatments.
View Article and Find Full Text PDFJ Craniofac Surg
July 2025
Department of Otolaryngology-Head and Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Radionecrosis can occur in any irradiated area of the head and neck, and when it involves the laryngotracheal region, it may lead to a laryngoesophageal fistula, causing dysphagia, aspiration, and life-threatening bleeding. A 45-year-old male with renal cell carcinoma (RCC) was referred due to prolonged dysphagia, recurrent aspiration, and hemoptysis after radiation therapy for a metastatic cervical spine lesion. Laryngoscopy and CT scan revealed destruction of the posterior cricoid cartilage and the membranous trachea, with a fistula formed between the laryngotrachea and pharynx.
View Article and Find Full Text PDFVet Pathol
September 2025
University of Pennsylvania, Philadelphia, PA.
Canine extramedullary plasma cell tumors (EMPs) most commonly arise in the skin, oral cavity, rectum, and colon. This retrospective study describes the histopathological and immunohistochemical characteristics and associated clinical signs and outcomes of laryngeal and tracheal EMPs in dogs. Five tracheal and 5 laryngeal EMPs were diagnosed at the Penn Vet Diagnostic Laboratory.
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