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Objective: The objectives of this study were to quantify the variation in coincident stages of incisor, canine and molar eruption and tooth formation in modern humans and great apes and then to ask if any early fossil hominins showed a dental development pattern beyond the human range and/or clearly typical of great apes.
Design: Four stages of eruption and 18 stages of tooth development were defined and then scored for each developing tooth on radiographs of 159 once-free-living subadult great apes and on orthopantomographs of 4091 dental patients aged 1-23 years. From original observations, and from published images of eleven early fossil hominins, we then scored formation stages of permanent incisors when M1 was at root formation stage R¼-R½ and R¾-RC.
Results: Incisor and canine eruption/development was delayed in great apes relative to molar development when compared with humans but there was overlap in almost all anterior tooth stages observed. Molar crown initiation was generally advanced in great apes and delayed in humans but again, we observed overlap in all stages in both samples. Only two fossil hominin specimens (L.H.-3 from Laetoli, Tanzania and KNM-KP 34725 from Kanapoi, Kenya) showed delayed incisor development relative to M1 beyond any individuals observed in the human sample.
Conclusions: For certain tooth types, the distribution of formation stages in our samples showed evidence of generally advanced or delayed development between taxa. However, it would rarely if ever be possible to allocate an individual to one taxon or another on this basis.
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http://dx.doi.org/10.1016/j.archoralbio.2022.105549 | DOI Listing |
Pol Merkur Lekarski
September 2025
Kharkiv Clinical Hospital on Railway Transport No. 1 ≪Health Care Center≫ of Joint-Stock Company «Ukrainian Railways», Kharkiv, Ukraine.
Objective: Aim: The purpose was to identify the morphological features of the great saphenous vein in patients with chronic venous disease of the lower extremities undergoing treatment with endovenous high-frequency electric welding in automatic mode, endovenous laser ablation, and ultrasound-guided microfoam sclerotherapy.
Patients And Methods: Materials and Methods: The material for the comprehensive morphological study consisted of fragments of the great saphenous vein obtained from 32 patients with chronic venous disease of the lower extremities. The material was divided into three groups according to the endovenous treatment techniques applied.
PLoS One
September 2025
Department of Evolutionary Anthropology, University of Zurich, Zurich, Switzerland.
Research over the last 20 years has shed important light on the vocal behaviour of our closest living relatives, bonobos and chimpanzees, but mostly relies on qualitative vocal repertoires, for which quantitative validations are absent. Such data are critical for a holistic understanding of a species` communication system and unpacking how these systems compare more broadly with other primate and non-primate species. Here we make key progress by providing the first quantitative validation of a Pan vocal repertoire, specifically for wild bonobos.
View Article and Find Full Text PDFBull Math Biol
September 2025
Department of Mathematics and Faculty of Medicine, The University of Ottawa, Ottawa, ON, K1N 6N5, Canada.
Host defense and pathogen virulence interact and mutually shape each other's evolution. Host-pathogen co-evolutionary outcomes have potentially significant impacts on population dynamics and vice versa. To investigate host-pathogen interactions and explore the impact of micro-level co-evolutionary outcomes on macro-level epidemics, we develop a co-evolutionary model with a combined host-defense strategy.
View Article and Find Full Text PDFKardiologiia
September 2025
West China Hospital of Sichuan University, Department of Cardiovascular Surgery, Sichuan University.
A middle-aged female presenting with progressive heart failure was admitted to the emergency department. She had a history of mitral and aortic valve replacement and a reoperation involving the Konno procedure. Echocardiography suggested a possible paraprosthetic leakage, which was confirmed during surgery.
View Article and Find Full Text PDFMed Phys
September 2025
Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong SAR, China.
Background: Four-dimensional magnetic resonance imaging (4D-MRI) holds great promise for precise abdominal radiotherapy guidance. However, current 4D-MRI methods are limited by an inherent trade-off between spatial and temporal resolutions, resulting in compromised image quality characterized by low spatial resolution and significant motion artifacts, hindering clinical implementation. Despite recent advancements, existing methods inadequately exploit redundant frame information and struggle to restore structural details from highly undersampled acquisitions.
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