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Background: Low-grade fibromyxoid sarcoma is a rare painless neoplasm that primarily grows in young adults' proximal extremities and trunks. The lungs are infrequent sites for this type of sarcoma.
Case Presentation: We reported a 26-year-old female that presented with a chief complaint of chest pain from a few months ago to Kasra hospital, Tehran, Iran, in August 2021. Chest computed tomography (CT) showed a hypodense mass with a well-defined margin measuring 9.3 cm in the left upper lobe and multiple hypodense lesions with a lobulated appearance with a total diameter of 15.5 × 13.5 cm in the left lower lobe of the lung.
Conclusion: This is the largest case of primary pulmonary low-grade fibromyxoid sarcoma (30 × 28 × 7 cm), which seemed unresectable at first evaluation. Due to the extent of the tumor, left pneumonectomy was performed, leading to attenuation of symptoms and no recurrence at a six-month follow-up.
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http://dx.doi.org/10.1002/cnr2.1718 | DOI Listing |
Asian J Neurosurg
September 2025
Dr. Udayan's Laboratory, Vadodara, Gujarat, India.
Low-grade fibromyxoid tumors are very uncommon in children. A tumor of this type has never been reported in the posterior fossa to date. Such lesions may mimic more common lesions of the posterior fossa.
View Article and Find Full Text PDFJ Clin Pathol
August 2025
Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Aims: To investigate immunohistochemical expression of the E26 transformation-specific factors (ETS)-related gene () in a large number of soft tissue neoplasms using a tissue microarray technique.
Methods: 489 cases of soft tissue neoplasms, including benign and malignant entities, were collected from the files of the respective institutions and constructed into tissue microarrays. Tissue microarrays were stained for ERG immunohistochemistry using two antibodies, EP111 and EPR3864.
Medicine (Baltimore)
August 2025
Department of Pathology, Guangxi Medical University Cancer Hospital, Nanning, China.
Rationale: Dedifferentiated liposarcoma (DDLPS) is a subtype of sarcoma that originates from atypical lipomatous tumor/well-differentiated liposarcoma and undergoes varying degrees of dedifferentiation. DDLPS can occur either concurrently with or after atypical lipomatous tumor/well-differentiated liposarcoma, with the dedifferentiated component predominantly consisting of high-grade sarcomas. Notably, only approximately 10% of DDLPS cases present as purely low-grade sarcomas.
View Article and Find Full Text PDFDiscoveries (Craiova)
June 2025
Department of Radiodiagnosis, Homi Bhabha Cancer Hospital and Research Centre, Tata Memorial Centre, Homi Bhabha National Institute (HBNI), New Chandigarh, Punjab, India.
Low-grade fibromyxoid sarcoma (LGFMS) is a rare fibroblastic neoplasm with an indolent clinical course. It is a distinctive subclass of soft tissue sarcoma with metastasizing potential and sometimes a long interval between tumor presentation and metastasis. This case report describes a 60-year-old female with an unresectable pleural LGFMS initially misdiagnosed as malignant mesothelioma.
View Article and Find Full Text PDFRadiol Case Rep
September 2025
Radiólogo, Departamento de Radiología e Imágenes Diagnósticas, Fundación Valle del Lili, Cali, Colombia.
Malignant liver tumors in children are rare, accounting for only 0.5%-1.5% of all pediatric cancers.
View Article and Find Full Text PDF