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Whilst the electrocardiogram (ECG) is an essential tool for diagnosing cardiac electrical abnormalities, its characteristics are dependent on anatomical variability. Specifically variation in torso geometry affects relative positions of the leads with respect to the heart. We propose a novel pipeline that uses standard cardiac magnetic resonance images to reconstruct the torso and heart, and recreate the ECG considering torso and cardiac anatomy. This requires automated extraction of the torso contours. Our method combines an initial u-net segmenter with a second network that refines contours and removes spurious segments. The networks were evaluated on a cross validation study dataset and an independent test set. The use of two-channel input, including both original image and initial segmentation, in the refinement network significantly improved performance on the independent test set, reducing the Hausdorff distance from 9.1 pixels to 4.3 pixels and increasing Dice coefficient from 0.75 to 0.93. Clinical Relevance- This method can be utilized to allow ECG simulations with personalized torso geometry which has previously been demonstrated to significantly effect QRS parameters. A clinical tool can be developed using this method that accounts for torso geometry in ECG interpretation.
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http://dx.doi.org/10.1109/EMBC48229.2022.9871643 | DOI Listing |
Biosensors (Basel)
August 2025
Department of Biomedical Engineering, Yonsei University, Wonju 26493, Republic of Korea.
This study presents the development and the mechanical and clinical characterization of a flexible biodegradable chitosan-glycerol-graphite composite strain sensor for real-time respiratory monitoring, where the main material, chitosan, is derived and extracted from larvae shells. Chitosan was extracted using a sustainable, low-impact protocol and processed into a stretchable and flexible film through glycerol plasticization and graphite integration, forming a conductive biocomposite. The sensor, fabricated in a straight-line geometry to ensure uniform strain distribution and signal stability, was evaluated for its mechanical and electrical performance under cyclic loading.
View Article and Find Full Text PDFBiomed Phys Eng Express
August 2025
Department of Radiology, Stanford University, Stanford, CA, United States of America.
. Patient movement is an ever-present reality in any clinical imaging scenario. In the context of digital tomosynthesis, thoracic motion can profoundly impact the resulting image quality.
View Article and Find Full Text PDFJ Cancer Res Ther
April 2025
Department of Physics, School of Chemical and Physical Sciences, Lovely Professional University, Phagwara, Punjab, India.
Aim: The aim of the present study was to create an indigenous anthropomorphic heterogeneous female pelvis (AHFP) phantom for quality assurance and dosimetric audits in advance radiotherapy centers.
Material And Methods: The AHFP phantom was designed using paraffin wax, epoxy, water, polyvinyl chloride (PVC), and a hardener. A dosimetric audit was conducted using the fabricated phantom among four different hospitals.
J Biomech
August 2025
Musculoskeletal Biomechanics Research Lab, Department of Mechanical Engineering, McGill University, 845 Sherbrooke St. W, Montréal, Quebec H3A 0C3, Canada; Orthopaedic Research Lab, Montreal General Hospital, 1650 Cedar Ave (LS1.409), Montreal, Quebec H3G 1A4, Canada. Electronic address: mark.drisc
Biomechanical modelling studies have revealed the impact of passive mechanical properties of spinal soft tissues on spinal configuration. This study extends prior work by evaluating the involvement of trunk abdominal and intramuscular pressure (IMP), on spinal geometric compensation, using a validated finite element spine model. The model included the vertebrae, rib cage, IVD, pelvis, ligaments, abdominal cavity and abdominal and spinal muscles.
View Article and Find Full Text PDFEJNMMI Phys
May 2025
Department of Electronics and Information Systems, Medical Image and Signal Processing, Ghent University, Ghent, Belgium.
Background: The combination of longer axial field-of-view (AFOV) and time-of-flight positron emission tomography (PET) has significantly improved system sensitivity and, as a result, image quality. This study investigates a cost-effective extended AFOV PET system design using monolithic LYSO detectors with depth-of-interaction capabilities. These detectors, arranged in a vertical flat-panel geometry and positioned closer to the patient, enable superior spatial resolution while maintaining a compact and affordable system design.
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