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The current prospective longitudinal study evaluated brooding rumination as an intervening mechanism of the association between COVID-19-related stress and internalizing symptoms during the first year of the pandemic. Attention-deficit/hyperactivity disorder (ADHD) status and adolescent sex were tested as moderators of the indirect effect. Adolescents with and without ADHD (N = 238; M age = 16.74) completed rating scales of COVID-19 stress and both adolescents and parents completed ratings scales of internalizing symptoms in May/June 2020 (T1). In October/November 2020 (T2), adolescents reported on their brooding rumination. Adolescents and parents reported on internalizing symptoms again in March/April 2021 (T3). Covariates included participant characteristics and baseline symptoms. T1 self-reported COVID-19-related stress was associated with increased T3 self-reported anxiety (ab = 0.10), self-reported depression (ab = 0.07), and parent-reported depression (ab = 0.09) via T2 brooding rumination. The indirect effect did not differ for adolescents with and without ADHD or for female and male adolescents. Brooding rumination may be one mechanism to target to promote the mental health adjustment of adolescents during periods of high stress of the COVID-19 pandemic and future stressors.
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http://dx.doi.org/10.1007/s10578-022-01435-3 | DOI Listing |
Prog Neuropsychopharmacol Biol Psychiatry
September 2025
Department of Women's and Children's Health, SciLifeLab, Uppsala University, Sweden. Electronic address:
Estrogens are suggested to affect mood by binding to widespread estrogen receptors in the brain and therewith modulating a variety of neurosignaling pathways. Single nucleotide polymorphisms (SNPs) in the genes encoding estrogen receptors might influence these actions and thereby play a role in the genetic foundation of mood disorders. Several SNPs in the estrogen receptor 1 (ESR1) gene have been studied in relation to anxiety and depression, while confounders and interaction with psychosocial factors have largely been overlooked.
View Article and Find Full Text PDFPsychiatry Res
September 2025
Department of Clinical Sciences, Psychiatry, Lund University, Sölvegatan 19 - BMC I12, 221 84 Lund, Sweden. Electronic address:
Negative consequences of gambling problems have primarily been examined in terms of symptoms and impairment, with less focus on well-being, a key indicator of intra- and interpersonal functioning and a critical outcome in treatment. Additionally, the role of co-occurring psychopathology in this relation remains unclear. This study examined the relation between gambling problems and well-being in a large population-based sample of individuals who gamble (N = 1005; 52.
View Article and Find Full Text PDFJ Affect Disord
September 2025
Department of Public Health, Bartholins Allé 2, Aarhus University, 8000, Aarhus C, Denmark. Electronic address:
Purpose: To study the association between internalizing and externalizing symptoms and prosocial behavior at age 7 years and pubertal timing in boys and girls.
Methods: This cohort study included 11,090 children from the Puberty Cohort within the Danish National Birth Cohort (DNBC). Data on internalizing and externalizing symptoms and prosocial behavior was derived from a parent-reported Strengths and Difficulties Questionnaire (SDQ) at age 7 years, and categorized as normal (lowest 79th percent), at-risk (80th - 89th percent) or abnormal (≥90th percent).
Pediatr Allergy Immunol
September 2025
Food Allergy Referral Centre, Veneto Region, Department of Women and Child Health, Padua University Hospital, Padua, Italy.
This narrative review aimed to explore mental health issues among children with food-induced anaphylaxis (FIA) and their parents and to identify possible risk factors. A review of the scientific literature from 2005 to 2025 (MEDLINE, PubMed, PsycINFO) was done, and 31 papers were selected. Results were presented according to DSM-V diagnostic categories.
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