Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000201131DOI Listing

Publication Analysis

Top Keywords

author response
4
response association
4
association fecal
4
fecal plasma
4
plasma levels
4
levels short-chain
4
short-chain fatty
4
fatty acids
4
acids gut
4
gut microbiota
4

Similar Publications

Background: According to the Council of International Organizations and Medical Sciences (CIOMS) 2016, post-trial access (PTA) refers to the ethical imperative that requires the sponsor, researchers, and relevant public health authority, "to make available as soon as possible any intervention or product developed, and knowledge generated, for the population or community in which the research is carried out." Law, policy, and practical guidance for PTA has so far been vague but has recently attracted and increased attention in the context of benefit sharing of scientific research results with low- and middle-income countries (LMICs).Although the number of clinical trials conducted in the Sub Saharan (SSA) countries has increased in the past two decades, plans and practices for PTA are underreported.

View Article and Find Full Text PDF

l-Ascorbic acid exhibits paradoxical behavior as both antioxidant and pro-oxidant in cancer treatment, with mechanisms and optimal dosing remaining unclear. This in vitro study investigated l-ascorbic acid's effects on healthy lymphocytes and HL-60 leukemia cells using concentrations of 0.5-2 mg/mL for 6 and 24 h.

View Article and Find Full Text PDF

Objectives: This study aimed to investigate healthcare professionals' experiences with using the PRO Palliative Care questionnaire (PRO-Pall) to identify palliative care symptoms and problems in non-specialized palliative care settings among patients with heart, lung, and kidney disease, and cancer. The study also investigated the PRO-Pall's potential to ensure further initiatives and care.

Methods: A national, multicenter, observational study employing a mixed-methods approach.

View Article and Find Full Text PDF

Background: Emotion dysregulation is a central feature in trauma-associated disorders such as posttraumatic stress disorder (PTSD) and borderline personality disorder (BPD). However, it remains unclear whether emotion dysregulation is a transdiagnostic phenomenon closely linked to childhood trauma, or if disorder-specific alterations in emotion processing exist. Following a multimethodological approach, we aimed to assess and compare the reactivity to and regulation of emotions between patients with BPD and PTSD, as well as healthy controls, and identify associations with childhood trauma.

View Article and Find Full Text PDF