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http://dx.doi.org/10.1002/ajmg.a.62930 | DOI Listing |
Cancer Res Treat
September 2025
Department of Laboratory Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Purpose: In hormone receptor (HR)-positive, HER2-negative early breast cancer, gene expression testing facilitates treatment decisions. A next-generation sequencing (NGS)-based assay was developed to address test decentralization and underrepresentation of younger/premenopausal patients. We aimed to validate the long-term prognostic value of the NGS-based assay and analyze its quality control (QC) parameters.
View Article and Find Full Text PDFJ Cancer Educ
August 2025
Parasitic Disease Unit, FMC Medical Center, Nakhon Ratchasima, Thailand.
The ONCARE initiative, as presented by Dou et al., represents a timely and commendable national effort to enhance oncology education within Canadian undergraduate medical curricula. In this letter to the editor, we critically appraise the study's implications through critical appraisal and contextualize its findings within broader medical education paradigms.
View Article and Find Full Text PDFJMIR Res Protoc
August 2025
European Institute of Oncology, IRCCS, Milan, Italy.
Background: Over 50% of newly diagnosed patients with breast cancer are aged ≥65 years. Due to age-related factors and the presence of comorbidities, these patients are particularly vulnerable to developing cardiac toxicity associated with cancer treatments, which may lead to suboptimal interventions and undertreatment, resulting in poorer health outcomes, quality of life (QoL) deterioration, and increased health care costs. Given the underrepresentation of older patients with breast cancer in clinical trials and the increasing recognition of the impact of psychosocial and behavioral factors on cardiovascular disease onset, broader and interdisciplinary studies are required to develop new and innovative best practices for this clinical population.
View Article and Find Full Text PDFFront Psychol
July 2025
Institute of Cognitive Sciences and Technologies, National Research Council, Rome, Italy.
Introduction: This study investigated the relationship between pacifier use and early vocabulary development, specifically hypothesizing that pacifier use would correlate with a reduced overall vocabulary size and a specific underrepresentation of abstract words.
Methods: We recruited a sample of 98 typically developing children aged 18-36 months. Data collection included information on pacifier use, feeding habits, parenting styles, parental satisfaction, and vocabulary.
Int J Angiol
September 2025
Division of Pulmonary and Critical Care Medicine, Texas Tech University Health Sciences Center, El Paso, Texas.
There is an underrepresentation of Hispanic patients in studies examining right ventricular (RV) function in acute pulmonary embolism (PE). Although the prognostic value of RV dysfunction in acute PE is well established, there is no generalized definition of RV dysfunction. In this study, our aim was to identify echocardiographic parameters that predict short-term mortality in Hispanic patients with intermediate-risk acute PE.
View Article and Find Full Text PDF