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Article Abstract
A Rh-catalyzed weak chelation-guided C4-alkylation of indoles has been accomplished using cyclopropanols as an alkylating agent via the cascade C-H and C-C bond activation. The substrate scope, functional group tolerance, and late-stage mutation of drug molecules are the important practical features.
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| http://dx.doi.org/10.1021/acs.orglett.2c02265 | DOI Listing |
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Associate Professor, School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan, ROC. Electronic address:
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