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The incidence of sarcopenic obesity among adults aged ≥65 years is rising worldwide. Sarcopenic obesity is a high-risk geriatric syndrome defined as a gain in the amount of adipose tissue along with the age-related loss of muscle mass and strength or physical performance. Sarcopenic obesity is associated with increased risks of falls, physical limitations, cardiovascular diseases, metabolic diseases, and/or mortality. Thus, the identification of preventive and treatment strategies against sarcopenic obesity is important for healthy aging. Diet and exercise are the reasons for the development of sarcopenic obesity and are key targets in its prevention and treatment. Regarding weight reduction alone, it is most effective to maintain a negative energy balance with dietary calorie restriction and aerobic exercise. However, it is important to preserve skeletal muscle mass while reducing fat mass. Resistance exercise and appropriate protein supply are the main ways of preserving skeletal muscle mass, as well as muscle function. Therefore, in order to improve sarcopenic obesity, a complex treatment strategy is needed to limit energy ingestion with proper nutrition and to increase multimodal exercises. In this review, we focus on recently updated interventions for diet and exercise and potential future management strategies for Asian individuals with aging-related sarcopenic obesity. Geriatr Gerontol Int 2022; 22: 695-704.
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http://dx.doi.org/10.1111/ggi.14442 | DOI Listing |
J Frailty Aging
September 2025
Department of Geriatric Medicine, Klinikum Fürth, Fürth, Germany; Institute for Biomedicine of Ageing, Friedrich-Alexander-University, Erlangen-Nürnberg, Germany.
Purpose: Sarcopenia and sarcopenic obesity are defined by the loss of muscle strength and mass. Both diseases pose a growing global challenge. Their prevalences vary between studied populations.
View Article and Find Full Text PDFSurg Oncol
September 2025
Department of Diagnostic and Interventional Radiology, University Hospital Leipzig, Leipzig, Liebigstr. 20, 04103, Leipzig, Germany. Electronic address:
Introduction: Body composition including low skeletal muscle mass (LSMM) defined by skeletal muscle index (SMI) and subcutaneous and visceral adipose tissue (SAT and VAT) can be assessed using cross-sectional imaging techniques. Previous studies have shown promising prognostic value for several tumour entities, including esophageal cancer (EC). The aim of this study was to analyse possible associations of body composition parameters in patients with esophageal cancer undergoing curative treatment.
View Article and Find Full Text PDFInt J Gen Med
August 2025
Nutrition Department, Affiliated Hospital of Chengde Medical University, Chengde, People's Republic of China.
Purpose: This study aimed to evaluate the individual and joint associations of malnutrition and obesity on predicting the severity and prognosis of acute pancreatitis (AP).
Patients And Methods: A retrospective analysis of 240 AP patients was conducted. Malnutrition was diagnosed using Global Leadership Initiative on Malnutrition (GLIM) criteria.
J Frailty Sarcopenia Falls
September 2025
Healthy Ageing Programme, Alexandra Hospital, National University Health System, Singapore.
Objectives: The impact of sarcopenic obesity (SO) on frailty, cognition, and function compared to sarcopenia and obesity alone remains unclear. This study examined SO's effects on these domains in community-dwelling older adults.
Methods: We assessed 202 older adults (mean age 80.
Metabol Open
September 2025
Renal Division, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, China.
Background: Sarcopenic obesity (SO) combines reduced muscle mass and increased fat, elevating health risks in older adults. The triglyceride-glucose (TyG) index, a marker of insulin resistance, is associated with metabolic dysfunction. However, its role in predicting mortality in SO remains unclear.
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