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The anti-epidemic supply chain plays an important role in the prevention and control of the COVID-19 pandemic. Prior research has focused on studying the facility location, inventory management, and route optimization of the supply chain by using certain parameters and models. Nevertheless, uncertainty, as a vital influence factor, greatly affects the supply chain. As such, the uncertainty that comes with technological innovation has a heightened influence on the supply chain. Few studies have explicitly investigated the influence of technological innovation on the anti-epidemic supply chain under the COVID-19 pandemic. Hence, the current research aims to investigate the influences of the uncertainty caused by technological innovation on the supply chain from demand and supply, shortage penalty, and budget. This paper presents a three-level model of the anti-epidemic supply chain under technological innovation and employs an interval data robust optimization to tackle the uncertainties of the model. The findings are obtained as follows. Firstly, the shortage penalty will increase the costs of the objective function but effectively improve demand satisfaction. Secondly, if the shortage penalty is sufficiently large, the minimum demand satisfaction rate can ensure a fair distribution of materials among the affected areas. Thirdly, technological innovation can reduce costs. The technological innovation related to the transportation costs of the anti-epidemic material distribution center has a greater influence on the optimal value. Meanwhile, the technological innovation related to the transportation costs of the supplier has the least influence. Fourthly, both supply and demand uncertainty can influence costs, but demand uncertainty has a greater influence. Fifthly, the multi-scenario budgeting approach can decrease the calculation complexity. These findings provide theoretical support for anti-epidemic dispatchers to adjust the conservativeness of uncertain parameters under the influence of technological innovation.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281244 | PMC |
http://dx.doi.org/10.1007/s10479-022-04855-5 | DOI Listing |
Cuad Bioet
September 2025
Universidad Francisco de Vitoria. Pozuelo de Alarcón Madrid. España.
This article examines the ethical challenges posed by NBIC emerging and converging technologies (na-notechnology, biotechnology, artificial intelligence and information technologies, and cognitive sciences) from the perspective of personalist bioethics. Their biomedical and social applications are described, high-lighting the main values at stake: dignity, life, autonomy, vulnerability, and justice. Finally, guidelines are proposed, inspired by the principles of personalist bioethics: defense of human life, therapeutic totality, responsible freedom, and justice, to ensure that technological development remains at the service of the person and the common good.
View Article and Find Full Text PDFPLoS One
September 2025
School of Emergency Technology, Guangzhou Vocational College of Technology and Business, Guangzhou, China.
Under China's national sustainability strategy, the logistics industry is confronted with the imperative of high-quality green development. Given its status as the leading economic province and a national logistics hub, investigating green logistics development in Guangdong province holds paramount strategic importance. To comprehensively evaluate green logistics development efficiency of 21 cities in Guangdong from 2016 to 2022, this study employed the super-efficiency slacks-based measure model (Super-SBM) with undesirable outputs, the Global Malmquist-Luenberger (GML) productivity index and a four-quadrant analysis based on static and dynamic efficiency.
View Article and Find Full Text PDFPLoS One
September 2025
School of Economics and Business Administration, Chongqing University, Chongqing, China.
This study investigates the impact of data assets on enterprise persistent innovation using panel data from Chinese A-share listed firms from 2011 to 2022. The results indicate that data assets significantly enhance both the inputs and outputs of enterprise persistent innovation, with the findings remaining robust under endogeneity tests. Mediation analysis reveals that data assets influence enterprise persistent innovation through three key channels: process innovation, business innovation, and technological innovation.
View Article and Find Full Text PDFDiscov Nano
September 2025
Department of Rehabilitation Medicine, Rehabilitation Medical Center, Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Immunoelectron Microscopy (IEM) is a technique that combines specific immunolabeling with high-resolution electron microscopic imaging to achieve precise spatial localization of biomolecules at the subcellular scale (< 10 nm) by using high-electron-density markers such as colloidal gold and quantum dots. As a core tool for analyzing the distribution of proteins, organelle interactions, and localization of disease pathology markers, it has irreplaceable value, especially in synapse research, pathogen-host interaction mechanism, and tumor microenvironment analysis. According to the differences in labeling sequence and sample processing, the IEM technology system can be divided into two categories: the first is pre-embedding labeling, which optimizes the labeling efficiency through the pre-exposure of antigenic epitopes and is especially suitable for the detection of low-abundance and sensitive antigens; the second is post-embedding labeling, which relies on the low-temperature resin embedding (e.
View Article and Find Full Text PDFJ Robot Surg
September 2025
Department of Research and Innovation, Medway NHS Foundation Trust, Gillingham, ME7 5NY, UK.
Robotic surgery has transformed the field of surgery, offering enhanced precision, minimal invasiveness, and improved patient outcomes. This narrative review explores the multifaceted aspects of robotic surgery, examining the challenges, recent advances, and future prospects for its integration into healthcare. Our comprehensive analysis of 48 studies reveals significant geographic disparities in robotic surgery research and implementation, with 68.
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