Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
This case series investigates the association of a segmental, facial, antibody-associated brainstem sensory syndrome with the immune checkpoint inhibitor pembrolizumab.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274447 | PMC |
| http://dx.doi.org/10.1001/jamaneurol.2022.1824 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Exosomal miR-494 from Bone Marrow Mesenchymal Stem Cells Attenuates Ferroptosis and Enhances Spinal Cord Injury Repair by Modulating the SIRT1/HO-1 Pathway.
Mol Neurobiol
September 2025
Affiliated Zhongshan Hospital of Dalian University, No. 6 Jiefang Street, Zhongshan District, Dalian, Liaoning Province, 116001, People's Republic of China.
Spinal cord injury (SCI) is a severe traumatic disorder of the central nervous system, often resulting in partial or complete loss of sensory and motor functions. Ferroptosis, a lipid peroxidation-driven apoptotic process triggered by iron overload, has emerged as a novel form of programmed cell death and a focal point in post-SCI cell death research. Exosomes (Exo), as delivery vehicles, exhibit multiple advantages, including superior encapsulation capacity, high targeting efficiency, and enhanced blood-brain barrier penetration to reach the central nervous system.
View Article and Find Full Text PDFDevelopmental auditory deprivation in one ear impairs brainstem binaural processing and reduces spatial hearing acuity.
PLoS Biol
September 2025
Neuroscience Training Program, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America.
Early sensory experience can exert lasting perceptual consequences. For example, a brief period of auditory deprivation early in life can lead to persistent spatial hearing deficits. Some forms of hearing loss (i.
View Article and Find Full Text PDFA brain-wide map of neural activity during complex behaviour.
Nature
September 2025
Princeton University, Princeton, NJ, USA.
A key challenge in neuroscience is understanding how neurons in hundreds of interconnected brain regions integrate sensory inputs with previous expectations to initiate movements and make decisions. It is difficult to meet this challenge if different laboratories apply different analyses to different recordings in different regions during different behaviours. Here we report a comprehensive set of recordings from 621,733 neurons recorded with 699 Neuropixels probes across 139 mice in 12 laboratories.
View Article and Find Full Text PDFShort-term memory errors are strongly associated with a drift in neural activity in the posterior parietal cortex.
PLoS Biol
September 2025
Sensory and Motor Systems Neuroscience Group, Korea Brain Research Institute, Daegu, South Korea.
Understanding the neural mechanisms behind short-term memory (STM) errors is crucial for unraveling cognitive processes and addressing deficits associated with neuropsychiatric disorders. This study examines whether STM errors arise from misrepresentation of sensory information or decay in these representations over time. Using 2-photon calcium imaging in the posterior parietal cortex (PPC) of mice performing a delayed match-to-sample task, we identified a subset of PPC neurons exhibiting both directional and temporal selectivity.
View Article and Find Full Text PDFModulation of Auditory Cortex Activity in Salicylate-Induced Tinnitus Rats via Deep Brain Stimulation of the Inferior Colliculus.
Brain Behav
September 2025
Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton, UK.
Background: Tinnitus, a self-reported perceptual disorder, is currently believed to arise from maladaptive plasticity due to reduced sensory input. While deep brain stimulation (DBS) has shown promise in alleviating tinnitus-related behaviors, its effects on neuronal activity remain unclear. This study aimed to evaluate the spontaneous firing rates (SFRs) of the primary auditory cortex (A1) before and after DBS of the external cortex of the inferior colliculus (ECIC) in a rat model of tinnitus.
View Article and Find Full Text PDF