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Background: The Western Trauma Association has undertaken publication of best practice clinical practice guidelines on multiple trauma topics. These guidelines are based on scientific evidence, case reports, and best practices per expert opinion. Some of the topics covered by this consensus group do not have the ability to have randomized controlled studies completed because of complexity, ethical issues, financial considerations or scarcity of experience. Care of the pregnant trauma patient is one of these clinically complex situations that is based on physiologic data, standard trauma care, trauma care experience, and outcomes.
Methods: Review of multiple evidence- based guidelines, case reports, and expert opinion were compiled and reviewed.
Results: The algorithm is attached with detailed explanation of each step, supported by data if available.
Conclusion: Resuscitative and trauma care of the mother is the utmost priority.
Study Type: Algorithm, expert opinion, consensus.
Level Of Evidence: Diagnostic Tests/Criteria; Level III.
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http://dx.doi.org/10.1097/TA.0000000000003740 | DOI Listing |
Osteoporos Int
September 2025
Department of Rheumatology, Univ. Lille, CHU Lille, MABlab ULR 4490, 59000, Lille, France.
Medications like liraglutide 3.0 mg daily (Saxenda®; Novo Nordisk) and semaglutide 2.4 mg weekly (Wegovy®; Novo Nordisk), which are glucagon-like peptide-1 receptor agonists (GLP-1Ra), have been sanctioned for prolonged weight management in people living with obesity (PwO).
View Article and Find Full Text PDFHemasphere
September 2025
Hématologie et Hémostase Clinique, CHU de Brest Brest France.
Accelerated-phase (AP) or blast-phase (BP) myeloproliferative neoplasms (MPNs) are associated with dismal prognosis, with non-curative therapies such as hypomethylating agents (HMAs) considered in patients not eligible for intensive therapy, while some studies advocate for combination therapy with either ruxolitinib (RUXO) or venetoclax (VEN). To assess the relationship between treatment modalities and outcome, herein, we report a multicentric cohort of 149 patients (median age, 75 years) with AP/BP MPN not eligible for intensive therapy and/or allogeneic hematopoietic cell transplantation who received azacitidine (AZA) alone ( = 60) or in combination ( = 89; VEN [ = 51], RUXO [ = 27], or both [ = 9], isocitrate dehydrogenase inhibitors [ = 2]) between January 2019 and October 2023. With a median follow-up of 15 months, the median overall survival of the full cohort was 8.
View Article and Find Full Text PDFFront Neurol
August 2025
Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, MA, United States.
Background: Race associated differences and disparities in test scores, such as on neuropsychological measures, can complicate the interpretation of these test scores in student athletes following a concussion. It is unknown if there are race associated differences on the Sway Medical System, a battery that includes balance and cognitive tests for use in concussion management.
Purpose: To determine if there are race-associated differences in Sway Medical System balance and cognitive module scores among athletes undergoing preseason baseline testing.
Expert Rev Neurother
September 2025
Department of Neurology, Tallaght University Hospital (TUH)/The Adelaide and Meath Hospital incorporating the National Children's Hospital (AMNCH), Dublin, Ireland.
Introduction: Refractory migraine (RM) is characterized by a lack of response to both migraine-specific and repurposed treatments, significantly impairing quality of life. Risk factors for RM include, among others, overuse of symptomatic medications, nonadherence to treatment and comorbid conditions that limit the use of anti-migraine medications.
Areas Covered: This critical perspective addresses the diagnosis and management of patients with RM.
Bone Jt Open
September 2025
School of Medicine, University of Nottingham, Nottingham, UK.
Aims: The number of hip fractures is increasing, with significant mortality and morbidity, particularly among frail and comorbid patients. Enhanced recovery after surgery (ERAS) pathways have proven effective in elective orthopaedics, but this has not been investigated in people with hip fractures. This study aimed to identify current perioperative practice and develop a cohesive ERAS pathway tailored for hip fracture patients, to standardize and optimize care.
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