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We aimed to clarify the association between social activity and the development of dementia in older adults by hearing-impaired (HI) status. We applied a community-based prospective cohort study over 6 years as part of the Japan Gerontological Evaluation Study. The study included 53,549 participants aged 65 years and older who did not require long-term care. A baseline questionnaire survey was conducted; explanatory variables included physical and social activities, and the objective variable was dementia onset assessed by standardized protocol. Cox regression models were used to calculate hazard ratios (HRs) for dementia stratified by HI status. During the follow-up period, 6013 (11.2%) participants developed dementia. Analyses revealed increased dementia risk for participants with HI who participated in the following activities less than once a month: sport groups (HR 2.17, 95% CI 1.53-3.08), hobby groups (HR 1.70, 95% CI 1.34-2.17), going out (HR 2.19, 95% CI 1.51-3.17), and meeting with friends (HR 1.27, 95% CI 1.06-1.53). HI and lack of social activity increase the risk of dementia. The study results indicate that there is an association between low social activity and the development of dementia in people with HI; the strongest associations were found for low participation in sports and hobby groups.
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http://dx.doi.org/10.1177/23337214221100621 | DOI Listing |
Alzheimers Dement
September 2025
School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Camperdown, Sydney, New South Wales, Australia.
Introduction: Risperidone is approved for behaviors and psychological symptoms of dementia (BPSD), despite modest efficacy and known risks. Identifying responsive symptoms, treatment modifiers, and predictors is crucial for personalized treatment.
Method: A one-stage individual participant data meta-analysis of six randomized controlled trials (risperidone: n = 1009; placebo: N = 712) was conducted.
Eur Geriatr Med
September 2025
Department of Social Science, Center for Gerontology and Social Science, Research Institute, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.
Purpose: To investigate the longitudinal association between chronic pain and decline in activity of daily living (ADL) among community-dwelling older adults aged ≥ 60 years.
Methods: In this systematic review of prospective longitudinal studies with narrative synthesis, a comprehensive literature search was conducted using PubMed and Embase using free-text words and MeSH terms on February 3, 2025. Longitudinal studies that quantitatively assessed ADL at two or more time points and pain at least once were included.
J Prof Nurs
September 2025
Department of Applied Social Sciences, Technological University of the Shannon Midlands Midwest, Limerick, Ireland. Electronic address:
Effective scholarly writing is essential for academic success, yet it often presents challenges, including feelings of isolation and imposter syndrome. These challenges can lead to avoidance and procrastination, impeding progress in graduate studies and publications. In response to these common struggles, a virtual writing community called TUS WEWRITE! was piloted for twenty master's and PhD students and research-active faculty and administrative staff at the Technological University of the Shannon (TUS) Midlands Midwest in Ireland.
View Article and Find Full Text PDFToxicon
September 2025
Instituto Nacional de Pesquisas da Amazônia - INPA.
Social wasps make up a significant part to the diversity of the Hymenoptera order, one of the most varied insect groups. Beyond their ecological importance, these insects use their venom for defense, protecting their colonies. The venom of social wasps are rich in biologically active substances, including biogenic amines, peptides, proteins, enzymes, allergens, and volatile compounds.
View Article and Find Full Text PDFBehav Brain Res
September 2025
School of Psychology, Zhejiang Normal University, Jinhua, China, 321004; College of Economics and Management, Zhejiang Normal University, Jinhua, China, 321004. Electronic address:
Micro-charity, with its ease of dissemination, is an effective way to support public welfare. Gratitude has been shown to promote prosocial behavior. However, its specific role in driving micro-charity sharing, particularly the underlying neural correlates, remains unclear.
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