Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Objective: Programming plays an important role in the outcome of deep brain stimulation (DBS) for Parkinson's disease (PD). This study introduced a new application for functional zonal image reconstruction in programming.
Methods: Follow-up outcomes were retrospectively compared, including first programming time, number of discomfort episodes during programming, and total number of programming sessions between patients who underwent image-reconstruction-guided programming and those who underwent conventional programming. Data from 142 PD patients who underwent subthalamic nucleus (STN)-DBS between January 2017 and June 2019 were retrospectively analyzed. There were 75 conventional programs and 67 image reconstruction-guided programs.
Results: At 1-year follow-up, there was no significant difference in the rate of stimulus improvement or superposition improvement between the two groups. However, patients who underwent image reconstruction-guided programming were significantly better at the first programming time, number of discomfort episodes during programming, and total number of programming sessions than those who underwent conventional programming.
Conclusion: Imaging-guided programming of directional DBS leads was possible and led to reduced programming time and reduced patient side effects compared with conventional programming.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226297 | PMC |
| http://dx.doi.org/10.3389/fneur.2022.916658 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Implementation of a midwifery preceptor program in Sierra Leone: a qualitative evaluation using the Consolidated Framework for Implementation Research.
BMC Glob Public Health
September 2025
Connell School of Nursing, Boston College, Chestnut Hill, MA, USA.
Background: Sierra Leone has the world's third highest incidence of maternal mortality, with 443 deaths per 100,000 live births. Strengthening the country's midwifery workforce is essential to providing adequate maternal healthcare and reducing preventable perinatal mortality. In support of this goal, we developed and implemented a midwifery preceptor program (MPP) to train experienced midwives to effectively mentor new and student midwives.
View Article and Find Full Text PDFGenomic and clinical epidemiology of SARS-CoV-2 in coastal Kenya: insights into variant circulation, reinfection, and multiple lineage importations during a post-pandemic wave.
BMC Glob Public Health
September 2025
Kenya Medical Research Institute (KEMRI) - Wellcome Trust Research Programme (KWTRP), Kilifi, Kenya.
Background: Between November 2023 and March 2024, coastal Kenya experienced another wave of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections detected through our continued genomic surveillance. Herein, we report the clinical and genomic epidemiology of SARS-CoV-2 infections from 179 individuals (a total of 185 positive samples) residing in the Kilifi Health and Demographic Surveillance System (KHDSS) area (~ 900 km).
Methods: We analyzed genetic, clinical, and epidemiological data from SARS-CoV-2 positive cases across pediatric inpatient, health facility outpatient, and homestead community surveillance platforms.
Effectiveness comparison of an indicated child-centered group prevention program for disruptive behavior problems in children with vs. without co-occurring emotional problems.
BMC Psychol
September 2025
Behavioral Epidemiology, Institute of Clinical Psychology and Psychotherapy, TUD Dresden University of Technology, Chemnitzer Straße 46, 01187, Dresden, Germany.
Background: Disruptive behavior and emotional problems - especially anxiety - are common in children and frequently co-occur. However, the role of co-occurring emotional problems in disruptive behavior intervention response is unclear. This study aimed to compare the effectiveness of an indicated prevention program in children with disruptive behavior problems with vs.
View Article and Find Full Text PDFHealth-related quality of life among adults with hypertension with or without anxiety and depression: estimates from a national US data.
Health Qual Life Outcomes
September 2025
Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, 11149, Saudi Arabia.
Distinct evolutionary trajectories of subgenomic centromeres in polyploid wheat.
Genome Biol
September 2025
Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101, Beijing, China.
Background: Centromeres are crucial for precise chromosome segregation and maintaining genome stability during cell division. However, their evolutionary dynamics, particularly in polyploid organisms with complex genomic architectures, remain largely enigmatic. Allopolyploid wheat, with its well-defined hierarchical ploidy series and recent polyploidization history, serves as an excellent model to explore centromere evolution.
View Article and Find Full Text PDF