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In the present work, the compatibility relationship on the failure criteria between aluminium and polymer was established, and a mechanics-based model for a three-layered sandwich panel was developed based on the M-K model to predict its Forming Limit Diagram (FLD). A case study for a sandwich panel consisting of face layers from AA5754 aluminium alloy and a core layer from polyvinylidene difluoride (PVDF) was subsequently conducted, suggesting that the loading path of aluminium was linear and independent of the punch radius, while the risk for failure of PVDF increased with a decreasing radius and an increasing strain ratio. Therefore, the developed formability model would be conducive to the safety evaluation on the plastic forming and critical failure of composite sandwich panels.
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http://dx.doi.org/10.3390/ma15124140 | DOI Listing |
Environ Sci Pollut Res Int
July 2025
Department of Civil Engineering, Aarupadai Veedu Institute of Technology, Vinayaka Mission's Research Foundation (Deemed to be University), Tamil Nadu, Chennai, 603104, India.
Expanded polystyrene (EPS) concrete presents considerable promise as a sustainable construction material, providing both structural and ecological advantages. In terms of structural integrity, EPS core sandwich wall panels (SWP) demonstrate impressive mechanical properties, as evidenced by load testing on samples. The initial crack loads were recorded between 11.
View Article and Find Full Text PDFViruses
June 2025
Infectious Diseases Translational Research Programme and Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545, Singapore.
At least three betacoronaviruses have spilled over from bats to humans and caused severe diseases, highlighting the threat of zoonotic transmission. Thus, it is important to enhance surveillance capabilities by developing tools capable of detecting a broad spectrum of bat-borne betacoronaviruses. Three monoclonal antibodies (mAbs) targeting the nucleocapsid (N) protein were generated using recombinant N proteins from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV).
View Article and Find Full Text PDFACS Omega
July 2025
Escuela de Ingeniería Forestal, Instituto Tecnológico de Costa Rica, Cartago Apartado 159-7050, Costa Rica.
The utilization of composite sandwich panels (CSP) with a core composed of wood or natural fibers presents a sustainable option for building insulation to address climate change. This study aims to produce and assess CSP thermoacoustic insulators by examining their physical, mechanical, acoustic, and thermal characteristics. The panels, with thicknesses of 12 and 19 mm, are constructed using cores of balsawood or pineapple leaves () (PALF) variety M2 and melina wood () as veneer.
View Article and Find Full Text PDFMethods Cell Biol
July 2025
Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Université Paris Saclay, Villejuif, France; Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Université Paris Cité, Sorbonne Université, Inserm U1138, Institut Universitaire de France, Par
Dendritic cells (DCs) are professional antigen-presenting cells that are pivotal in operating tumor immunosurveillance and orchestrating anticancer immune responses. Endowed with phagocytic and migratory capacities, DCs can capture and process tumor antigens, travel to lymphoid organs and prime naïve T cells, altogether leading to the clonal expansion of cytotoxic T lymphocytes (CTLs) that can specifically target and lyse cancer cells. Additionally, DCs contribute to the formation of immunological memory, ensuring durable therapeutic effects and long-term surveillance against tumor recurrence.
View Article and Find Full Text PDFMethods Mol Biol
July 2025
Flemish Institute for Technological Research (VITO), Environmental Intelligence, Mol, Belgium.
Multi-array technology allows for multiplex profiling of protein biomarker panels through sandwich immunoassays with high sensitivity, excellent reproducibility, and wide dynamic range. We describe here the detection of secreted cytokine levels in media of an in vitro stimulated human alveolar cell model that vary in a dose- and time-dependent manner. Depending on the analyte concentrations, several sample dilutions can be tested on a single multi-spot plate.
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