Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Functional reconstruction of the upper extremity has traditionally involved tendon transfer or pedicled muscle transfer. The gracilis free functional muscle transfer remains as an excellent option for restoration of finger flexion. Here, we provide a case report of a 35-year-old man diagnosed with left forearm high-grade epithelioid sarcoma who underwent innervated free gracilis transfer and a secondary free flap, the profunda artery perforator flap, through a single donor-site incision to expand soft tissue coverage. Postoperatively, there were no complications reported. At 8-month follow-up, the patient had Musculoskeletal Tumor Score of 22/30, and a Quick Disabilities of the Arm, Shoulder, and Hand score of 34/100.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187175 | PMC |
| http://dx.doi.org/10.1097/GOX.0000000000004367 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Facial nerve pathology: emerging strategies for regeneration and functional restoration.
J Mater Chem B
September 2025
Nebraska Translational Research Center (NTRC), Department of Growth and Development, College of Dentistry, University of Nebraska Medical Center, Joseph D. & Millie E. Williams Science Hall, 525 S 42nd St, Room No 3.0.010, Omaha, NE 68105-6040, USA.
Facial nerve injuries cause significant functional impairments, affect facial expressions, speech, and overall quality of life. This article explores advances in facial nerve regeneration, encompassing both conventional and emerging therapeutic strategies. The regenerative process involves Wallerian degeneration, axonal regrowth, and target muscle reinnervation, where the distal axon degrades and the proximal axon initiates sprouting to restore connectivity.
View Article and Find Full Text PDFMyostatin knockout mice muscle derived exosome inhibited dexamethasone-induced muscle atrophy.
Int Immunopharmacol
September 2025
Department of Animal Science, College of Agricultural, Yanbian University, Yanji 133002, China; Jilin Provincial Key Laboratory of Transgenic Animal and Embryo Engineering, Yanbian University, Yanji 133002, China. Electronic address:
Objective: Long-term administration of dexamethasone (DEX) to treat severe inflammation or autoimmune disorders often result in skeletal muscle atrophy and functional decline. Exosomes facilitate intercellular communication by transferring bioactive molecules, reflecting the characteristics of their tissue of origin. Myostatin-knockout (MSTN) mice exhibit muscle hypertrophy, and their muscle-derived exosomes (KO-EXOs) retain this phenotype.
View Article and Find Full Text PDFFree Gracilis Muscle Transfer in the Nerve-Depleted Patient: Reconsidering the Deep Temporal Nerve.
Laryngoscope
September 2025
Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology/Head and Neck Surgery, University of North Carolina, North Carolina, USA.
The choice of a donor nerve to innervate a free gracilis muscle transfer (FMGT) is more complicated in patients with a history of previous facial paralysis surgeries. This case report describes the use of the deep temporal nerve to successfully power a FMGT in a nerve-depleted patient.
View Article and Find Full Text PDFReconstruction of hip flexion after arthroscopic iliopsoas tendon release using free functional muscle.
JPRAS Open
September 2025
Department for Plastic Surgery, Hand Surgery-Burn Center, Division for Plexus Surgery, University Hospital RWTH Aachen, Pauwelsstraße 30, Aachen, 52074 North Rhine-Westphalia, Germany.
We present the case of a physically active 50-year-old patient who underwent an arthroscopic release of the iliopsoas tendon due to a snapping hip. Postoperatively, active hip flexion was severely weakened. As a consequence patient had no stable gait pattern and was unable to continue her sports and physical activities.
View Article and Find Full Text PDFA Minimally Invasive Method for Generating a Syngeneic Orthotopic Mouse Model of Lung Cancer.
J Vis Exp
August 2025
Department of Neuroscience and Pharmacology, Carver College of Medicine, University of Iowa; Department of Radiation Oncology, Holden Comprehensive Cancer Center, University of Iowa; Geminii, Inc.
Non-small cell lung cancer (NSCLC) continues to be the number one cause of cancer-related death for both women and men worldwide. More information needs to be gathered to understand the interactions between cancer cells, the immune system, the microenvironment within each tumor, and the host tissue to develop more effective treatment modalities. Reported here is a simple, repeatable method for inducing cancer within the mouse lung, allowing for the monitoring of tumor growth from early to late-stage disease.
View Article and Find Full Text PDF