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Background: Breast augmentation with autologous fat grafting was widely used. However, it is unclear how does this kind of surgery affect the morphologic change of breast. This study aimed to explore the change of nipple and inframammary fold (IMF) levels, which are important aesthetic landmarks of breast that further explore whether this kind of surgery could correct the asymmetry of nipple and IMF.
Methods: Preoperative and postoperative measurements were performed in the patients who received fat grafting with or without fasciotomy. The position levels of nipple and IMF were measured. The preoperative and postoperative discrepancies and the difference of these levels after surgery were also calculated.
Results: As for the IMF asymmetry, in the fasciotomy plus fat grafting group, the asymmetry was significantly reduced after surgery, while there was no significant difference in the fat grafting group. As for the nipple asymmetry, fat grafting could not correct the asymmetry in both fasciotomy plus fat grafting group and fat grafting group. As for the morphological change after surgery, both nipple and IMF were descended significantly after surgery. The descending range of IMF in the preoperative higher group was larger than the preoperative lower group. On the preoperative IMF higher side, descending degree of IMF was significantly larger in the fasciotomy plus fat grafting group than fat grafting group.
Conclusions: Fat grafting with fasciotomy can improve IMF asymmetry but cannot improve nipple asymmetry. Both IMF and nipple were lowered somehow after surgery, which might be related to the breast enlargement.
Level Of Evidence Iv: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
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http://dx.doi.org/10.1007/s00266-022-02959-8 | DOI Listing |
Transplant Cell Ther
September 2025
Division of Pharmacy, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Background: Pediatric patients undergoing hematopoietic stem cell transplant (HSCT) are at high risk for fungal infections including Candida, Aspergillus, and Mucorales necessitating the use of broad-spectrum antifungal agents such as posaconazole for prophylaxis and at times for treatment of invasive fungal infections. When first approved, posaconazole was limited to an immediate release oral suspension, which exhibited unreliable absorption dependent on co-administration with high fat meals. During HSCT, patients commonly have significant nausea, vomiting, and decreased enteral intake making this formulation particularly challenging.
View Article and Find Full Text PDFPoult Sci
August 2025
Jiangxi Provincial Key Laboratory of Poultry Genetic Improvement, Institute of Biological Technology, Nanchang Normal University, Nanchang, 330032, China. Electronic address:
Excessive abdominal fat deposition (AFD) in poultry reduces meat yield and efficiency. The gut microbiota regulates AFD through shifts in microbial composition and the production of metabolites. Reduced microbial diversity and fat-promoting taxa (e.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Otolaryngology-Head and Neck Surgery, Nihon University School of Medicine, Tokyo, Japan.
Glottic insufficiency results from impaired vocal fold contact, leading to a gap between the folds and manifesting as hoarseness and respiratory difficulties. Vocal folds injection is a commonly utilized therapeutic approach to rectify this gap by augmenting vocal folds volume; however, the optimal injectable material remains undetermined. Dedifferentiated fat cells (DFATs), derived from mature adipocytes, exhibit robust proliferative capacity and multipotency, establishing them as potential candidates for treating glottic insufficiency.
View Article and Find Full Text PDFFront Surg
August 2025
Department on Anesthesia and Surgery, Faculty of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.
Patulous Eustachian Tube (PET) dysfunction is a rare condition characterized by an abnormally open Eustachian tube, leading to symptoms such as autophony, auditory fullness, and pulsatile tinnitus. This case report describes a 48-year-old female weighing 72.4 kilograms who developed persistent autophony and hearing her own breathing and heartbeat sounds following significant weight loss after sleeve gastrectomy.
View Article and Find Full Text PDFAesthetic Plast Surg
September 2025
Department of Surgical Science, Medical School, Plastic and Reconstructive Surgery, Tor Vergata" University, 00133, Rome, Italy.
Background: The author presents his own experience using breast implants (BIs) or fat grafting, commonly called lipofilling (LPF), to correct breast hypoplasia.
Objectives: Compare the aesthetic results obtained in a study group (SG) using BIs in breast hypoplasia correction with those of a control group (CG) treated with LPF, analyzing the influence of breast and chest deformities (tuberous breast, breast volume differences/asymmetries, nipple-areola complex asymmetry, pectus excavatum, and carinatum) in the outcomes.
Methods: A randomized, open-label controlled study was performed.