Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Background: Improvement in visual naming abilities throughout the childhood and adolescence supports development of higher-order linguistic skills. We investigated neuronal circuits underlying improvement in the speed of visual naming with age, and age-related dynamics of these circuits.

Methods: Response times were electronically measured during an overt visual naming task in epilepsy patients undergoing stereo-EEG monitoring. Coherence modulations among pairs of neuroanatomic parcels were computed and analyzed for relationship with response time and age.

Results: During the overt visual naming task, mean response time (latency) significantly decreased from 4 to 23 years of age. Coherence modulations during visual naming showed that increased connectivity between certain brain regions, particularly that between left fusiform gyrus/left parahippocampal gyrus and left frontal operculum, is associated with improvement in naming speed. Also, decreased connectivity in other brain regions, particularly between left angular and supramarginal gyri, is associated with decreased mean response time. Further, coherence modulations between left frontal operculum and both left fusiform and left posterior cingulate gyri significantly increase, while that between left angular and supramarginal gyri significantly decrease, with age.

Conclusion: Naming speed continues to improve from pre-school years into young adulthood. This age-related improvement in efficiency of naming environmental objects occurs likely because of strengthened direct connectivity between semantic and phonological nodes, and elimination of intermediate higher-order cognitive steps.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160526PMC
http://dx.doi.org/10.3389/fnins.2022.867021DOI Listing

Publication Analysis

Top Keywords

visual naming
24
coherence modulations
16
response time
12
naming
9
neuronal circuits
8
overt visual
8
naming task
8
connectivity brain
8
brain regions
8
regions left
8

Similar Publications

The purpose of this study was to examine the effects of interfering with verbal and visual mediation in groups that received different training sequences in the intraverbal naming task. Experiment 1 examined the effects of disrupting verbal mediation during the image-matching test. Participants were assigned to one of four groups.

View Article and Find Full Text PDF

Animals communicate information primarily via their calls, and directly using their vocalizations proves essential for executing species conservation and tracking biodiversity. Conventional visual approaches are frequently limited by distance and surroundings, while call-based monitoring concentrates solely on the animals themselves, proving more effective and straightforward than visual techniques. This paper introduces an animal sound classification model named SeqFusionNet, integrating the sequential encoding of Transformer with the global perception of MLP to achieve robust global feature extraction.

View Article and Find Full Text PDF

Self-phosphorylating DNAzyme DK1 enables programmable multi-analyte readout via PfAgo.

Biosens Bioelectron

September 2025

Department of Biological Sciences, Faculty of Science, National University of Singapore, 117543, Singapore; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, 117597, Singapore; Precision Medicine Translational Research Programme (TRP), Yong Loo Lin School

DNAzymes possessing kinase-like activities have long held theoretical promise, yet their practical implementation has remained significantly limited. Notably, DNAzyme kinase 1 (DK1), discovered over two decades ago, exhibits a unique self-phosphorylation capability upon encountering specific substrates like ATP, but its broad-based and programmable applications have not yet been fully realized. In this study, we innovatively couple DK1's autophosphorylation mechanism with the PfAgo to establish a novel programmable cascade sensing platform named RASTEN (Robust pfAgo-based Strategy for POC Testing Non-nucleic Acid and Nucleic Acid).

View Article and Find Full Text PDF

High Efficiency Labeling of nerve Fibers in cleared tissue for light-sheet microscopy.

J Neurosci Methods

September 2025

European Laboratory for Non-linear Spectroscopy, via Nello Carrara 1, 50019 Sesto Fiorentino, Italy; National Institute of Optics -National Research Council (CNR-INO), 50125 Sesto Fiorentino, Italy. Electronic address:

Background: Tissue clearing techniques combined with light-sheet fluorescence microscopy (LSFM) enable high-resolution 3D imaging of biological structures without physical sectioning. While widely used in neuroscience to determine brain architecture and connectomics, their application for spinal cord mapping remains more limited, posing challenges for studying demyelinating diseases like multiple sclerosis. Myelin visualization in cleared tissues is particularly difficult due to the lipid-removal nature of most clearing protocols, and alternative immunolabeling approaches failed to reach satisfying results.

View Article and Find Full Text PDF

Understanding and controlling the nucleation and growth processes of gold clusters are crucial for advancing the nucleation theory and targeted cluster synthesis. While mass spectrometry has revealed the intermediate species formed during the growth process, the overall structural evolution remains unclear due to a lack of crystallographic information. In this study, we examined a new synthetic method for thiolate-protected gold clusters in their embryonic stage.

View Article and Find Full Text PDF