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Infective endocarditis and relationship with diabetes mellitus - Patient characteristics, microbial etiology and mortality.
Infection
September 2025
The Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Inge Lehmanns Vej 7, 16th floor, Copenhagen, 2100, Denmark.
Purpose: Infective endocarditis (IE) has been associated with severe outcomes when complicated by diabetes mellitus (DM). We aimed to report characteristics, microbial etiology, and mortality for patients with IE stratified by DM from a nationwide cohort.
Methods: We used Danish registries, and patients with first-time IE (2010-2020) were stratified by DM.
[OverView of infectious and non-infectious diseases in French Polynesia in 2025].
Med Trop Sante Int
July 2025
Unité des maladies infectieuses et tropicales et CIC Inserm 1424, Centre hospitalier de Cayenne, Cayenne, Guyane.
Tahiti or the "myth of Paradise", Bora Bora, "the Pearl of the Pacific". Who has never wanted to take a plane and come and land on the heavenly beaches of Polynesia, a French territory at the antipodes of mainland France lost in the middle of the Pacific? However, we do not imagine that 60% of Polynesians live below the metropolitan low-income threshold or that life expectancy is lower than that of the mainland due to the high prevalence of cardiovascular diseases with three quarters overweight population.In addition to non-transmissible metabolic diseases, various pathologies common to temperate countries present specificities in Polynesia, leading to sometimes different management and medical reasoning.
View Article and Find Full Text PDFAdvances and Prospects in the Diagnosis and Treatment of Blood Culture-Negative Infective Endocarditis.
Rev Cardiovasc Med
August 2025
The Second Clinical College of Fujian Medical University, 362000 Quanzhou, Fujian, China.
Blood culture-negative infective endocarditis (BCNE) constitutes an important subtype of infective endocarditis. Despite the rarity of BCNE, this subtype poses a significant diagnostic challenge and promotes a high mortality rate. Recent advances in diagnostic modalities have facilitated the rapid identification of BCNE.
View Article and Find Full Text PDFDevelopment and validation of a novel score to predict adverse outcomes in paediatric congenital mitral regurgitation (PRIMARY): a multicentre cohort study.
EClinicalMedicine
October 2025
Department of Cardiothoracic Surgery, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, China.
Background: Paediatric patients who underwent surgery for mitral regurgitation (MR) have a high risk of recurrence or death; however, no prediction tool has been developed to risk-stratify this challenging subpopulation.
Methods: In this multicentre cohort study, paediatric patients undergoing surgery for congenital MR in Shanghai Children's Medical Center in January 1st, 2009-December 31st, 2022 were included for analysis while those had a combination with infective endocarditis, anomalous left coronary artery from the pulmonary artery, rheumatic valvular disease, connective tissue disease, or single ventricle were excluded. A Cox regression model predictive of the primary outcome (a composite of mortality or mitral valve [MV] re-operation) was derived and converted to a point-based risk score.
A 5-Year Epidemiological Study of Monomicrobial Enterococcal Bloodstream Infection in a Population-Based Cohort.
Open Forum Infect Dis
September 2025
Division of Public Health, Infectious Diseases, and Occupational Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA.
Background: The incidence, epidemiology, and clinical characteristics of enterococcal bloodstream infection (BSI) have not previously been studied on a population-based level in the United States.
Methods: We utilized the Expanded Rochester Epidemiology Project medical records linkage system to conduct a contemporary 5-year, retrospective, population-based study of monomicrobial enterococcal (ME) BSI among adult residents of 8 counties in southeast Minnesota from January 1, 2018 to December 31, 2022.
Results: A total of 109 cases of ME-BSI were identified.