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Article Abstract
Heterocyclic aromatic compounds containing an imine (C[double bond, length as m-dash]N) bond such as benzimidazoles and benzothiazoles are important active pharmaceutical ingredients. The synthesis of 2-aryl-1-benzimidazoles and 2-arylbenzothiazoles in good to excellent yields was achieved by reacting 2-aminoaromatics with various benzaldehyde derivatives catalysed by the commercial laccases Novoprime and Suberase® at room temperature and in the presence of atmospheric oxygen.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090715 | PMC |
| http://dx.doi.org/10.1039/c8ra07377e | DOI Listing |
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