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http://dx.doi.org/10.3389/fphys.2022.871586 | DOI Listing |
Int J Mol Sci
April 2023
Department of Biomedical and Biotechnological Sciences, University of Catania, Via S. Sofia 64, 95123 Catania, Italy.
The voltage-dependent anion channel (VDAC) is the primary regulating pathway of water-soluble metabolites and ions across the mitochondrial outer membrane [...
View Article and Find Full Text PDFKidney360
October 2022
Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic Rochester, Minnesota.
Background: Mitochondrial injury occurs in and underlies acute kidney injury (AKI) caused by ischemia-reperfusion and other forms of renal injury. However, to date, a comprehensive analysis of this issue has not been undertaken in heme protein-induced AKI (HP-AKI). We examined key aspects of mitochondrial function, expression of proteins relevant to mitochondrial quality control, and mitochondrial ultrastructure in HP-AKI, along with responses to heme in renal proximal tubule epithelial cells.
View Article and Find Full Text PDFFront Physiol
April 2022
Department of Biological, Geological and Environmental Sciences, University of Catania, Catania, Italy.
Front Physiol
September 2021
Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, United States.
Future Med Chem
September 2020
Department of Cell Biology, Nestlé Research, Lausanne, 1015, Switzerland.