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The childhood obesity epidemic has persisted for over three decades, which has presented serious social, economic and health consequences worldwide. For researchers and policy makers alike, cycling has been a promising focus over recent years for developing long-term physically active lifestyles in urban environments, in addition to contributing to the global quest to combat climate change. Promoting cycling thus presents a win-win situation not just for individuals' well-being, but for multiple involved sectors such as public health, transport ministry and environmental agencies. For children, cycling promotes exercise engagement, active transport opportunities, motor skill development and social interaction. However, across European cities, there are considerable discrepancies in the uptake of cycling amongst children. To understand and subsequently promote children's cycling behavior, it is crucial that the complex social, physical and policy environment, and their interrelationships, are considered. Therefore, in this perspective article, we adopt the socio-ecological model to gain insight into how children's cycling behavior is shaped at the interpersonal, organizational and community level embedded within city policies, relevant to increase future cycling participation in children. Our perspective is based on a review of cycling policies of two European cities, Amsterdam (Netherlands) and Newcastle (UK), where stark contrasts in children's cycling participation can be observed. Our findings show that cycling policies in Amsterdam have mainly contributed to comprehensive organizational level changes, for example, cycling infrastructure development within the city, whereby these initiatives have made significant progress at the community level where cycling has become part of the "Dutch culture". Hence, cycling is a more common transportation mode among children in Amsterdam than in Newcastle. In Newcastle, policies primarily focus on organizational or community level changes, and progress has recently been accelerated in response to COVID-19. In addition to differences, we have also identified similar challenges in the two cities, such as the urgency to support uptake of cycling for children with low socio-economic background or challenges related to cultural differences. We also propose a "shared (cycle-)path" for policy makers and researchers as working together is crucial in producing multi-component interventions at a policy level that recognize individual, as well as interpersonal, community and organizational factors.
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http://dx.doi.org/10.3389/fpubh.2022.864883 | DOI Listing |
J Cell Mol Med
September 2025
Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China.
Diminished ovarian reserve (DOR) poses significant challenges in reproductive health, with emerging evidence implicating DNA damage repair pathways. While GADD45A is a critical regulator of DNA repair, cell cycle and apoptosis, its role in DOR pathogenesis remains unexplored. We employed transcriptome sequencing, qPCR and Western Blot analyses to compare GADD45A expression in granulosa cells (GCs) between DOR patients and controls.
View Article and Find Full Text PDFPediatr Obes
October 2025
National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland, USA.
Background: The National Health and Nutrition Examination Survey provides nationally representative data on child obesity using measured height and weight. Due to COVID-19, the NHANES August 2021-August 2023 cycle had design changes and smaller sample sizes for certain race/Hispanic origin groups. The objective is to explore sex and race/Hispanic origin-specific childhood obesity trends.
View Article and Find Full Text PDFSci Total Environ
September 2025
Center for Climate and Carbon Cycle Research, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea; Division of Energy & Environment Technology, KIST School, University of Science and Technology, Seoul 02792, Republic of Korea. Electronic address:
Neonicotinoid insecticides have been identified as significant contributors to the decline of pollinators. To evaluate potential exposure of pollinators to neonicotinoids in South Korea, 79 honey samples and 27 pollen samples were obtained from agricultural, mountain, and urban areas. These samples were analyzed for 17 compounds, including neonicotinoids and their metabolites using liquid chromatography coupled with mass spectrometry.
View Article and Find Full Text PDFNutr Clin Pract
September 2025
Department of Pediatrics, Mayo Clinic, Rochester, Minnesota, USA.
Home parenteral nutrition (HPN) is a life-sustaining therapy traditionally used as a bridge to enteral autonomy or intestinal transplantation. Increasingly, it is used for intractable feeding intolerance (IFI), which can occur near the end of life (EOL) in children with severe neurological impairment (SNI). In these cases, HPN use differs from its historical role and requires tailored outpatient planning.
View Article and Find Full Text PDFInt J Obes (Lond)
September 2025
Department of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, China.
Objective: To systematically evaluate the association between anthropometric parameter and myopia in children and adolescents.
Methods: PubMed, Web of Science, EBSCO, Embase, CNKI, CBM, WanFang Data, and VIP databases were searched from inception to June, 2025. We collected cross-sectional studies on the association between anthropometric parameter and myopia in children and adolescents aged 0-25 years, including body mass index (BMI) and weight-adjusted waist index (WWI).