Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Contact dermatitis is a continuous growing environmental and occupational health problem. It results in high costs for health care systems and the economy due to productivity loss. Moreover, it has a huge impact on the quality of life of patients. The immune response to contact allergy is very complex and not totally elucidated. Recently unique pathways preferentially activated by different allergens were identified. As for a lot of chronic itch disorders, antihistamines are ineffective for allergic contact dermatitis, suggesting a non-histaminergic itch. The precise mechanisms that underlie the development of itch in ACD remain poorly defined. This short review addresses the most recent insights in pruritus in ACD, opening perspectives for future therapies.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974693 | PMC |
| http://dx.doi.org/10.3389/falgy.2021.702488 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Retrospective Review of Dermal Safety Studies of Organic Sunscreens.
J Drugs Dermatol
September 2025
Background: Sunscreens can reduce skin cancer and sunburn. Recent studies on dermal penetration have raised concerns about the safety of sunscreens with organic ultraviolet (UV) filters.
Objective: The aim of the retrospective study was to assess the dermal safety of chemical sunscreens containing the chemical filters avobenzone, octocrylene, homosalate, and octisalate.
The therapeutic efficacy of mesenchymal stem cells and their extracellular vesicles in the treatment of diverse skin diseases.
Front Immunol
September 2025
Department of Dermatology and Venereology, Medical University of Bialystok, Bialystok, Poland.
This review presents the current knowledge on the potential of mesenchymal stem cells (MSCs) and their extracellular vesicles (EVs) in the treatment of various skin diseases such as psoriasis, atopic dermatitis, contact dermatitis, systemic sclerosis, graft-versus-host disease, alopecia areata, and systemic lupus erythematosus. MSCs can modulate the immune response and release growth factors and cytokines that promote tissue regeneration and healing and reduce inflammation. In turn, EVs' ability to transport various biological molecules, including microRNAs (miRNAs), makes them potential therapeutic agents.
View Article and Find Full Text PDFIrritant Contact Dermatitis Induced by Compound Clobetasol Propionate in a Patient with Undiagnosed Type 2 Diabetes Mellitus.
Clin Cosmet Investig Dermatol
August 2025
Department of Dermatology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People's Republic of China.
Irritant contact dermatitis (ICD) is a common inflammatory skin condition caused by direct cytotoxic effects of irritants on the epidermis. Topical corticosteroids, while effective for treating inflammatory dermatoses, may paradoxically induce adverse skin reactions when misused. This case highlights ICD triggered by self-administration of compound clobetasol propionate ointment, exacerbated by undiagnosed type 2 diabetes mellitus (T2DM).
View Article and Find Full Text PDF[A case of occupational allergic contact dermatitis caused by sinomenine hydrochloride].
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
August 2025
Outpatient Department of Changzhou Center for Disease Control and Prevention, Changzhou 213022, China.
Sinomenine hydrochloride is an alkaloid preparation commonly used in clinical practice in traditional Chinese medicine, and allergic reactions induced by occupational exposure to it are relatively rare in clinical settings. This article analyzes a case of allergic contact dermatitis in a medical worker after occupational exposure to sinomenine hydrochloride. The patient developed generalized skin rashes with the fingertips as the initial site three months after exposure to sinomenine hydrochloride.
View Article and Find Full Text PDFT helper and IL-20 cytokine signatures distinguish atopic dermatitis from contact dermatitis subtypes.
J Eur Acad Dermatol Venereol
September 2025
Department of Dermatology, Cliniques universitaires Saint-Luc, Université catholique de Louvain (UCLouvain), Brussels, Belgium.