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In the field of medical informatics, sleep staging is a challenging and time consuming task undertaken by sleep experts. The conventional method for sleep staging is to analyze Polysomnograms (PSGs) recorded in a sleep lab, but the sleep monitoring with polysomnography (PSG) severely degrades the sleep quality. Despite recent significant progress in the development of automatic sleep staging methods, building a good model still remains a big challenge for sleep studies due to the data-variability and data-inefficiency issues. Electrooculograms (EOGs) and electrocardiograms (ECGs) and are much easier to record and may offer an attractive alternative for home sleep monitoring. PSGs from the Sleep Heart Health Study database were used. This study aims to establish an new automatic sleep staging algorithm by using electrooculogram (EOG) and electrocardiogram (ECG).First, the heart rate variability (HRV) is extracted from EOG with the Weight Calculation Algorithm and an 'NRRD' RR interval detection algorithm. Second, three feature sets were extracted from HRV segments and EOG segments: time-domain features, frequency-domain features and nonlinear-domain features. The frequency domain features and nonlinear-domain features were extracted by using Discrete Wavelet Transform, Autoregressive (AR), and Power Spectral entropy, and Refined Composite Multiscale Dispersion Entropy. Third, a new 'Parallel Fusion Method' (PFM) for sleep stage classification is proposed. Three kinds of feature sets from EOG and HRV segments are fused by using PFM. Fourth, Extreme Gradient Boosting (XGBoost) is employed for sleep staging.Our experimental results show significant performance improvement on automatic sleep staging on the target domains achieved with the new sleep staging approach. The performance of the proposed method is tested by evaluating the average accuracy, Kappa coefficient. The average accuracy of sleep classification results by using XGBoost classification model with PFM is 83% and the kappa coefficient is 0.7. Experimental results show that the performance of the proposed method is competitive with the most current methods and results, and the recognition rate of S1 stage is significantly improved.As a consequence, it would enable one to improve the quality of automatic sleep staging models when the EOG and HRV signals are fused, which can be beneficial for monitor sleep quality and keep abreast of health conditions. Besides, our study provides good research ideas and methods for scholars, doctors and individuals.
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http://dx.doi.org/10.1088/1361-6579/ac647b | DOI Listing |
Commun Biol
September 2025
Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Sleep is a complex behavior regulated by various brain cell types. However, the roles of brain-resident macrophages, including microglia and CNS-associated macrophages (CAMs), particularly those derived postnatally, in sleep regulation remain poorly understood. Here, we investigated the effects of resident (embryo-derived) and repopulated (postnatally derived) brain-resident macrophages on the regulation of vigilance states in mice.
View Article and Find Full Text PDFZhonghua Jie He He Hu Xi Za Zhi
September 2025
Neuromuscular diseases are often accompanied by various types of sleep-related breathing disorders, which can exacerbate the underlying condition and are associated with a poor prognosis. Early identification is essential, and interventions such as non-invasive ventilation, oxygen therapy, and respiratory rehabilitation should be initiated promptly to mitigate disease progression and improve outcomes. Nevertheless, the rates of missed and misdiagnosed cases remain common in clinical practice.
View Article and Find Full Text PDFMenopause
September 2025
Bayer Consumer Care, Basel, Switzerland.
Importance: Sleep disturbances are common during and after the menopause transition, with potential effects on morbidity and quality of life; however, they may be underdiagnosed and undertreated.
Objective: We carried out a systematic literature review to investigate the prevalence and impact of sleep disturbances associated with menopause on women's health-related quality of life across the stages of menopause.
Evidence Review: Searches were conducted in PubMed and Excerpta Medica Database to identify articles published between 2013 and 2023 containing evidence for the impact of sleep quality on health-related quality of life and the epidemiology of sleep disturbances in women in menopause.
Arch Psychiatr Nurs
October 2025
Research Center for Social Determinants of Health, Jahrom University of Medical Sciences, Jahrom, Iran. Electronic address:
Background: Metabolic syndrome is a widespread disease in the general population. The purpose of this study is to investigate the global prevalence of metabolic syndrome in the community of people with bipolar disorder through a systematic review and meta-analysis.
Methods: In this study, we conducted a systematic review and meta-analysis using electronic databases, including PubMed, Scopus, Web of Science, Embase, ScienceDirect, and the Google Scholar search engine.
J Integr Neurosci
August 2025
Neurological Institute of Jiangxi Province and Department of Neurology, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, and Xiangya Hospital of Central South University at Jiangxi, 330038 Nanchang, Jiangxi, China.
Sleep paralysis, colloquially known as "ghost pressing" is a state of momentary bodily immobilization occurring either at the onset of sleep or upon awakening. It is characterized by atonia during rapid eye movement (REM) sleep that continues into wakefulness, causing patients to become temporarily unable to talk or move but possessing full consciousness and awareness of their surroundings. Sleep paralysis is listed in the International Classification of Sleep Disorders, 3rd Edition (ICSD-3) as a parasomnia occurring during REM sleep that be classified as either isolated or narcolepsy-associated.
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