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Article Abstract

A 56-year-old woman with a history of connective tissue disease developed fever, and () was detected in blood cultures. Therefore, treatment with vancomycin (VCM) was initiated. Since her blood cultures persistently detected despite peripheral intravenous catheter replacement and VCM treatment, concomitant treatment with gentamicin (GM) was started. Blood cultures then became negative. Persistent bacteremia responded to combination therapy with VCM and GM. This combination therapy may increase the risk of developing renal dysfunction, but the risk can be mitigated by appropriate therapeutic drug monitoring (TDM) and dose adjustments to achieve successful treatment.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8934234PMC
http://dx.doi.org/10.1155/2022/8725102DOI Listing

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