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The negative effects of SARS-CoV-2 infection on the musculoskeletal system include symptoms of fatigue and sarcopenia. The aim of this study is to assess the impact of COVID-19 on foot muscle strength and evaluate the reproducibility of peak ankle torque measurements in time by using a custom-made electronic dynamometer. In this observational cohort study, we compare two groups of four participants, one exposed to COVID-19 throughout measurements and one unexposed. Peak ankle torque was measured using a portable custom-made electronic dynamometer. Ankle plantar flexor and dorsiflexor muscle strength was captured for both feet at different ankle angles prior and post COVID-19. Average peak torque demonstrated no significant statistical differences between initial and final moment for both groups (p = 0.945). An increase of 4.8%, p = 0.746 was obtained in the group with COVID-19 and a decrease of 1.3%, p = 0.953 was obtained in the group without COVID-19. Multivariate analysis demonstrated no significant differences between the two groups (p = 0.797). There was a very good test−retest reproducibility between the measurements in initial and final moments (ICC = 0.78, p < 0.001). In conclusion, peak torque variability is similar in both COVID-19 and non-COVID-19 groups and the custom-made electronic dynamometer is a reproducible method for repetitive ankle peak torque measurements.
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http://dx.doi.org/10.3390/s22052073 | DOI Listing |
Respir Med
September 2025
Department of Medicine, Pulmonary and Critical Care Medicine, Albany Medical Center, Albany, NY.
Study Objectives: Mandibular repositioning appliances (MRAs) are widely used for obstructive sleep apnea (OSA) and snoring, but their safety profile remains underexplored. This study analyzes adverse events associated with MRAs using the FDA Manufacturer and User Facility Device Experience (MAUDE) database.
Methods: A retrospective review of the MAUDE database identified adverse events related to MRAs under the product code "LRK" from January 1, 2015, to February 8, 2025.
J Prosthet Dent
September 2025
Professor, Department of Restorative Dentistry, School of Dentistry, Federal University of Juiz de Fora (UFJF), Juiz de Fora, MG, Brazil. Electronic address:
Statement Of Problem: Whether the unfavorable crown-to-implant ratio of extrashort implants and the use of splinted versus nonsplinted crowns affects marginal bone loss and implant survival remains unclear.
Purpose: The purpose of this split-mouth randomized clinical trial was to evaluate the effect of splinting on survival rates and clinical and radiographic parameters associated with prostheses supported by extrashort implants in the posterior region of atrophic mandibles over a 3-year follow-up period.
Material And Methods: Sixty extrashort implants (5 mm in length) were placed in 10 participants.
Neuromodulation
September 2025
Department of Neurology, Institute of Neurosciences Kolkata, Kolkata, India. Electronic address:
Background: Vagus nerve stimulation (VNS) is approved as an adjunctive therapeutic intervention in neurologic conditions, including epilepsy and primary headache disorders. Transauricular VNS (tVNS) is increasingly used as a method for noninvasively activating the vagus nerve. However, the central neurophysiologic effects of tVNS are not well understood.
View Article and Find Full Text PDFInjury
August 2025
Department of Orthopedics and Traumatology, Bahçeşehir University Faculty of Medicine, Istanbul, Turkey. Electronic address:
Background: Coronoid fractures significantly impact elbow stability, yet limited biomechanical data exists comparing fixation methods for different fracture types. This study aimed to compare the biomechanical performance of threaded K-wire versus cortical screw fixation in O'Driscoll type 2 and 3 coronoid fractures.
Methods: Twenty-eight synthetic ulnar bones were divided into four groups (n = 7 each): Type 2 with K-wire fixation, Type 2 with screw fixation, Type 3 with K-wire fixation, and Type 3 with screw fixation.
Bioengineering (Basel)
July 2025
DOE Joint BioEnergy Institute, Emeryville, CA 94608, USA.
Electroporation-mediated gene delivery is a cornerstone of synthetic biology, offering several advantages over other methods: higher efficiencies, broader applicability, and simpler sample preparation. Yet, electroporation protocols are often challenging to integrate into highly multiplexed workflows, owing to limitations in their scalability and tunability. These challenges ultimately increase the time and cost per transformation.
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