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http://dx.doi.org/10.1111/add.15864 | DOI Listing |
J Magn Reson Imaging
September 2025
Department of Neurology, Dell Medical School, University of Texas at Austin, Austin, Texas, USA.
Background: Cerebrovascular reactivity reflects changes in cerebral blood flow in response to an acute stimulus and is reflective of the brain's ability to match blood flow to demand. Functional MRI with a breath-hold task can be used to elicit this vasoactive response, but data validity hinges on subject compliance. Determining breath-hold compliance often requires external monitoring equipment.
View Article and Find Full Text PDFTransfusion
September 2025
Department of Human Genetics, The University of Utah School of Medicine, Salt Lake City, Utah, USA.
Background: Although blood group variation was first described over a century ago, our understanding of the genetic variation affecting antigenic expression on the red blood cell surface in many populations is lacking. This deficit limits the ability to accurately type patients, especially as serological testing is not available for all described blood groups, and targeted genotyping panels may lack rare or population-specific variants.
Study Design And Methods: Here, we perform serological assays across 24 antigens and whole genome sequencing on 100 Omanis, a population underrepresented in genomic databases.
Exp Aging Res
September 2025
Department of Rehabilitation, Naragakuen University, Nara, Japan.
Purpose: Patients with Alzheimer's disease (AD) lose the ability to manage their medications as the disease progresses. Several methods have been used to administer medication to patients at home using Internet of Things (IoT) devices for rehabilitation, but no studies have yet been published investigating the factors that influence the success or failure of this approach in older adults and patients with AD. Therefore, this study aimed to investigate differences in medication-related behaviors and their influencing factors in older adults, both with and without AD, using IoT.
View Article and Find Full Text PDFEur J Intern Med
September 2025
Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy; Istituti Clinici Scientifici ICS Maugeri - S.p.A.-Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Scientifico di Telese Terme, Telese, Italy. Electronic address:
The fraction that the elderly represent in the world's population is growing rapidly; numerous alterations that impact all organs and systems, including the immune system, are related to aging. A complex process common in the elderly, known as immunosenescence, is characterized by a decreased ability to respond to vaccination as well as an increased risk of bacterial and viral infections, autoimmune, cardiovascular and neurodegenerative diseases. These processes are associated with alterations in the innate and adaptive immune system and lead to a condition of chronic low-grade inflammation, referred to as inflammaging.
View Article and Find Full Text PDFPestic Biochem Physiol
November 2025
Henan Engineering Laboratory of Pest Biological Control/College of Plant Protection, Henan Agricultural University, Zhengzhou 450046, People's Republic of China.
Henosepilachna vigintioctopunctata represents a significant economic pest, typically controlled through the use of chemical insecticides. The introduction of RNA interference (RNAi) technology has opened new avenues for biopesticide development, leading to the identification of various genes that are crucial for the growth and development of insects. However, the efficient screening of target genes in H.
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