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Glaucoma is a silent disease that leads to vision loss or irreversible blindness. Current deep learning methods can help glaucoma screening by extending it to larger populations using retinal images. Low-cost lenses attached to mobile devices can increase the frequency of screening and alert patients earlier for a more thorough evaluation. This work explored and compared the performance of classification and segmentation methods for glaucoma screening with retinal images acquired by both retinography and mobile devices. The goal was to verify the results of these methods and see if similar results could be achieved using images captured by mobile devices. The used classification methods were the Xception, ResNet152 V2 and the Inception ResNet V2 models. The models' activation maps were produced and analysed to support glaucoma classifier predictions. In clinical practice, glaucoma assessment is commonly based on the cup-to-disc ratio (CDR) criterion, a frequent indicator used by specialists. For this reason, additionally, the U-Net architecture was used with the Inception ResNet V2 and Inception V3 models as the backbone to segment and estimate CDR. For both tasks, the performance of the models reached close to that of state-of-the-art methods, and the classification method applied to a low-quality private dataset illustrates the advantage of using cheaper lenses.
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http://dx.doi.org/10.3390/s22041449 | DOI Listing |
Cureus
August 2025
Acute Medicine, Southend University Hospital, Mid and South Essex NHS Foundation Trust, Southend-on-Sea, GBR.
Adenocarcinoma of the lung is the most common type of lung cancer and is classified as one of the non-small cell lung cancers. It typically arises in the peripheral regions of the lungs, affecting the dense glandular tissues. Most patients diagnosed with pulmonary adenocarcinoma are current or former smokers and present with nonspecific respiratory symptoms such as a persistent cough and shortness of breath.
View Article and Find Full Text PDFZhonghua Yan Ke Za Zhi
September 2025
The prevalence of normal tension glaucoma (NTG) in China stands at 1%. The inappropriate demarcation of normal intraocular pressure values may lead to misdiagnosis. The Glaucoma Group of Ophthalmology Branch of Chinese Medical Association released the consensus on the diagnosis and treatment of NTG in 2019, which established important clinical guidelines for the NTG management.
View Article and Find Full Text PDFZhonghua Yan Ke Za Zhi
September 2025
Primary angle-closure glaucoma (PACG) is a prevalent clinical condition. In 2019, the Glaucoma Group of Ophthalmology Branch of Chinese Medical Association released the consensus opinions on the diagnosis and treatment of PACG, providing crucial guidance for clinical practice. Since significant new research on PACG has emerged over the past five years, both the Glaucoma Group of Ophthalmology Branch of Chinese Medical Association and the Glaucoma Group of Chinese Ophthalmologist Association have collaborated to conduct extensive evidence-based discussions to attain an updated consensus on the classification, diagnostic approaches, and treatment principles for PACG in China, which may serve as a reference for clinical practitioners.
View Article and Find Full Text PDFZhonghua Yan Ke Za Zhi
September 2025
Aier Glaucoma Institute, Hunan Engineering Research Center for Glaucoma with Artificial Intelligence in Diagnosis and Application of New Materials, Changsha Aier Eye Hospital, Changsha 410015, China.
As the world's leading irreversible blinding eye disease, glaucoma is predominantly managed with pharmaceutical interventions in clinical practice. However, long-term use of traditional eye drops containing preservatives (e.g.
View Article and Find Full Text PDFAm J Ophthalmol
September 2025
Singapore Eye Research Institute, Singapore National Eye Centre, Singapore; Duke-NUS Graduate Medical School, Singapore; Department of Ophthalmology, Emory University School of Medicine, Emory University; Department of Biomedical Engineering, Georgia Institute of Technology/Emory University, Atlanta
Purpose: To characterize the 3D structural phenotypes of the optic nerve head (ONH) in patients with glaucoma, high myopia, and concurrent high myopia and glaucoma, and to evaluate their variations across these conditions.
Design: Retrospective cross-sectional study.
Participants: A total of 685 optical coherence tomography (OCT) scans from 754 subjects of Singapore-Chinese ethnicity, including 256 healthy (H), 94 highly myopic (HM), 227 glaucomatous (G), and 108 highly myopic with glaucoma (HMG) cases METHODS: We segmented the retinal and connective tissue layers from OCT volumes and their boundary edges were converted into 3D point clouds.