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Article Abstract
https://bit.ly/3mmFbQn.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864625 | PMC |
| http://dx.doi.org/10.1183/23120541.00485-2021 | DOI Listing |
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Penicillin allergy de-labelling implementation intervention in a UK hospital: a process evaluation, the patient experience.
JAC Antimicrob Resist
August 2025
Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Background: Penicillin allergy (penA) records are common, but true penA is rare. PenA records are associated with broad spectrum antibiotic prescribing and negative patient outcomes. We developed a behavioural intervention package to support inpatient penicillin allergy de-labelling (PADL) delivered by a multi-profession non-allergist workforce to remove incorrect penA records from medical and surgical adult inpatients in a UK hospital.
View Article and Find Full Text PDFFirst-line treatment with ceftriaxone for infection less likely to be prescribed to patients with a penicillin allergy label: a retrospective audit of medical records.
Sex Health
July 2024
Canberra Sexual Health Centre, Canberra Health Services, Garran, ACT, Australia; and School of Medicine and Psychology, Australian National University, Canberra, ACT, Australia.
Background Gonorrhoea notifications have increased substantially in Australia over the past decade. Neisseria gonorrhoeae is already highly resistant to several antibiotics and so, alternatives to first-line treatment are generally strongly discouraged. The penicillin allergy label (AL) on patient medical records has previously been shown to influence prescribing practices, to the detriment of best-practice management and antimicrobial stewardship.
View Article and Find Full Text PDFBeta-lactam allergy risk stratification in a maternity population in Australia: Scope for allergy de-labelling.
Aust N Z J Obstet Gynaecol
October 2024
Infection Prevention and Control, The Royal Women's Hospital, Melbourne, Victoria, Australia.
Background: Unconfirmed beta-lactam allergy in pregnant people has been associated with higher morbidity, unnecessary exposure to broad-spectrum antibiotics and prolonged hospitalisation. There are no published data on beta-lactam allergies in pregnant people in Australia.
Aims: The aim was to describe patient-reported beta-lactam allergies and appropriateness for antibiotic allergy de-labelling in a maternity cohort in Australia.
Penicillin Allergy label - the unmet needs - causes and potential solutions.
Eur Ann Allergy Clin Immunol
December 2022
Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, U.K.
Penicillin allergy is the most prevalent drug allergy. Its overdiagnosis has been associated with inappropriate antibiotic prescribing, increased antimicrobial resistance, worse clinical outcomes, and increased healthcare costs. 403 inpatients were audited against National Institute of Clinical Excellence (NICE) Clinical Guidance 183 (CG183) on diagnosis, investigations, documentation, and management of penicillin allergy.
View Article and Find Full Text PDFmyonecrosis in a pediatric patient with a self-reported penicillin allergy.
J Assoc Med Microbiol Infect Dis Can
December 2021
Division of Infectious Diseases, Immunology and Allergy, Children' Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
Infections with are especially rare in pediatric patients. is the most common cause of spontaneous myonecrosis and is usually associated with comorbid malignancy. Treatment of choice for cases of myonecrosis is prompt and thorough surgical debridement and antimicrobial therapy with high dose penicillin.
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