Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: The two key mechanisms affected by internet gaming disorder (IGD) are cognitive and reward processing. Despite their significance, little is known about neurophysiological features as determined using resting-state electroencephalography (EEG) source functional connectivity (FC).
Methods: We compared resting-state EEG source FC within the default mode network (DMN) and reward/salience network (RSN) between patients with IGD and healthy controls (HCs) to identify neurophysiological markers associated with cognitive and reward processing. A total of 158 young male adults (79 patients with IGD and 79 HCs) were included, and the source FC of the DMN and RSN in five spectral bands (delta, theta, alpha, beta, and gamma) were assessed.
Results: Patients with IGD showed increased theta, alpha, and beta connectivity within the DMN between the orbitofrontal cortex and parietal regions compared with HCs. In terms of RSN, patients with IGD exhibited elevated alpha and beta connectivity between the anterior cingulate gyrus and temporal regions compared with HCs. Furthermore, patients with IGD showed negative correlations between the severity of IGD symptoms and/or weekly gaming time and theta and alpha connectivity within the DMN and theta, alpha, and beta connectivity within the RSN. However, the duration of IGD was not associated with EEG source FC.
Conclusions: Hyper-connectivities within the DMN and RSN may be considered potential state markers associated with symptom severity and gaming time in IGD.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386438 | PMC |
| http://dx.doi.org/10.1017/S0033291722000137 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Subcutaneous Allergen-Specific Immunotherapy for Allergic Rhinitis: Divergent IgA Responses in Nasal Mucosa and Blood With Validation of B Cell Class-Switching in Lymph Nodes and Blood.
Clin Transl Allergy
September 2025
Division of Ear, Nose, and Throat Diseases, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Background: Subcutaneous immunotherapy (SCIT) has been a cornerstone treatment for allergic rhinitis (AR) for over 50 years, consistently demonstrating symptom reduction and modulation of immune responses. Despite this, the underlying mechanisms responsible for the efficacy of SCIT remain incompletely understood, especially with regard to local immune responses in lymph nodes and nasal mucosa.
Aim: To determine the impact of SCIT treatment on immunoglobulin production in blood and nasal mucosa, as well as B cell class-switching in blood and lymph nodes.
[Clinical characteristics analysis of patients with IgD type systemic light chain amyloidosis].
Zhonghua Yi Xue Za Zhi
September 2025
Department of Hematology, Peking University People's Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematological Diseases, Beijing 100044, China.
To analyze the clinical characteristics of patients with IgD type systemic light chain (AL) amyloidosis. The patients diagnosed with IgD-type AL amyloidosis at Peking University People's Hospital and the First Affiliated Hospital of Dalian Medical University from June 2013 to April 2023 (IgD group) were retrospectively included. These patients were matched with non-IgD type AL amyloidosis patients using a 1∶4 propensity score (non-IgD group).
View Article and Find Full Text PDFMediating role of depression and gender in the relationship between daily video games exposure and internet gaming disorder (IGD) among college students.
BMC Psychol
August 2025
School of Mental Health, Bengbu Medical university, Bengbu, Anhui, China.
To investigate the relationship between daily Video Games exposure and Internet Gaming Disorder (IGD) with reference to college students, analyse the mediating role of Depression and gender, and provide a theoretical basis for the prevention and treatment of IGD in college students. Using cluster random sampling, 1527 college students were selected to join the study. A Demographic questionnaire, Internet Gaming Disorder Test-20 (IGD-20), and Patient Health Questionnaire-9 (PHQ-9) were adopted to investigate Video Games and Depression among college students.
View Article and Find Full Text PDFTraditional laboratory parameters and IFNγ-related biomarkers in the diagnosis and management of MAS.
Semin Arthritis Rheum
August 2025
Division of Rheumatology, ERN-RITA center, IRCCS Ospedale Pediatrico Bambino Gesù, Roma, Italy.
Objectives: To evaluate diagnostic and prognostic significance of traditional laboratory parameters of hyperinflammation and of the IFNγ-related biomarkers interleukin-18 (IL-18), CXCL9 and neopterin in macrophage activation syndrome (MAS) secondary to Still's disease (SD).
Methods: Forty-one patients with MAS and 24 patients with active pediatric SD from six Italian centers were enrolled. Samples were obtained at baseline (at initiation or within 48 hours of initiation of specific treatments) for MAS or active SD and at T1 (5-15 days from baseline) only from MAS.
Both online and face-to-face mindfulness meditation can change cortical structure in internet gaming disorder.
J Psychiatr Res
August 2025
Department of Psychology, Nanjing University, Nanjing, China. Electronic address:
Background: Mindfulness meditation (MM) has been shown to effectively alleviate symptoms of Internet Gaming Disorder (IGD) and improve neural functioning. However, it remains unclear whether both online and face-to-face MM can enhance cortical structure, a stable and reliable neural biomarker.
Methods: This study included 100 IGD patients randomly assigned to three groups: face-to-face MM (31 participants), online MM (38 participants), or progressive muscle relaxation (PMR) (31 participants).