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http://dx.doi.org/10.4187/respcare.09671 | DOI Listing |
Radiol Res Pract
August 2025
Department of Radiology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Idiopathic interstitial pneumonias (IIPs) are widespread interstitial lung diseases with no known cause. The diseases are characterized by a steady decline in lung function. To assess the patterns of IIPs and investigate the correlation between the extents of lung involvement on high-resolution computed tomography (HRCT) with spirometric findings in Tikur Anbessa Specialized Hospital (TASH) chest clinic, covering the period from February 2020 to February 2023.
View Article and Find Full Text PDFRespir Physiol Neurobiol
September 2025
Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, TX, USA; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA. Electronic address: DrTonyBabb@TexasHeal
We examined the exercise ventilatory response to heavy exercise (ventilation [V̇] and carbon dioxide elimination [V̇CO] relationship from ventilatory threshold to peak exercise) and operational lung volumes (end expiratory [EELV] and end inspiratory [EILV]) in older adults with and without obesity. Forty-nine older adults with (BMI: 33.9 ± 5.
View Article and Find Full Text PDFRespir Care
September 2025
Ms. Vieira, Dr. Lima, Dr. Pondofe, Ms. Maciel, Dr. da Fonsêca, Dr. Resqueti, and Dr. Fregonezi, are affiliated with the Departamento de Fisioterapia, PneumoCardioVascular Lab/HUOL and the Laboratório de Inovação Tecnológica em Reabilitação, Universidade Federal do Rio Grande do Norte, Natal,
Mechanical insufflation-exsufflation (MI-E) consists of increasing expiratory air flow, thereby promoting an increase in cough peak flow (CPF) and secretion clearance. Respiratory impairment, characterized by reduced lung volumes and ineffective cough, is the major cause of morbidity and mortality in patients with amyotrophic lateral sclerosis (ALS). This study aimed to assess the acute effects of MI-E on CPF and chest wall compartmental and operational volumes in patients with ALS.
View Article and Find Full Text PDFEur Respir Rev
July 2025
Department of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, China
Background: Limited evidence exists on air pollution's systemic impact on lung function and mediating biomarkers. This study comprehensively evaluated associations between air pollution, COPD and lung function, while exploring biomarker mediation.
Methods: A prospective analysis of 451 566 UK Biobank participants was conducted.
Am Surg
September 2025
Division of Trauma, Emergency Surgery and Surgical Critical Care, Los Angeles General Medical Center, Los Angeles, CA, USA.
BackgroundDriving pressure (ΔP), the difference between peak inspiratory pressure (PIP) or plateau pressure (Pplat) and positive end-expiratory pressure (PEEP), has been proposed as a better target for avoiding ventilator-induced lung injury (VILI) in mechanically ventilated patients. This study aimed to determine if lower dynamic ΔP would correlate with reduced mortality and lower incidences of VILI.MethodsA single-center retrospective analysis identified 237 trauma patients admitted in 2020 who underwent ≥48 hours of mechanical ventilation and survived ≥72 hours.
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